身体活动对血液循环维生素D水平的影响--对观察性和实验性研究的系统综述与meta分析  

Effects of PhysicalActivity on Vitamin D:A Systematic Review and Meta-analysis of Observational and Experimental Studies

作　　者：张景华 王柯[1] 曹振波[1] ZHANG Jinghua;WANG Ke;CAO Zhenbo(School of Kinesiology,Shanghai University of Sport,Shanghai 200438,China)

机构地区：[1]上海体育学院运动科学学院,上海200438

出　　处：《上海体育学院学报》2021年第10期81-96,共16页Journal of Shanghai University of Sport

基　　金：上海市2020年度“科技创新行动计划”自然科学基金面上项目(20ZR1454400)。

摘　　要：目的系统梳理身体活动对血液循环维生素D水平影响的观察性研究和实验性研究,为身体活动调节微量营养素代谢提供理论依据。方法检索自数据库建立至2020年11月30日PubMed、Embase、CochraneLibrary、中国知网等数据库中的观察性研究和实验性研究。根据纳入和排除标准筛选文献,并进行meta分析和系统综述。结果共纳入74篇文献,包括51篇观察性研究和23篇实验性研究。观察性研究meta分析结果显示,较高的身体活动水平与较低的维生素D缺乏风险显著相关。亚组分析结果表明:室外身体活动会显著降低维生素D缺乏风险,但室内身体活动无该效应;较高强度的身体活动与较低的维生素D缺乏风险显著相关,但低强度身体活动与之无相关性;不同季节身体活动均与较低的维生素D缺乏风险显著相关。实验性研究结果表明,急性运动和长期运动训练均可显著提高血液循环25-羟维生素D[25(OH)D]水平;亚组分析结果显示,耐力训练和抗阻联合耐力训练均能显著提高血清25(OH)D水平,但抗阻训练并无显著性效应。结论身体活动水平与血液循环维生素D水平之间呈显著正相关,且运动干预对血液循环维生素D营养状态具有有益作用。Objective To make a systematic review with meta-analysis on the effects of physical activity/exercise on vitamin D,and provide a theoretical evidence of regulating the micro-nutrients based on the observational and experimental studies.Methods Databases such as PubMed,Embase,Cochrane Library,and CNKI were searched for observational studies and experimental studies as of November 30,2020.Literatures were screened according to the inclusion and exclusion criteria,and were systematically reviewed with meta-analysis.Results 74 studies were eligible,including 51 observational studies and 23 experimental studies.The result of observational studies showed that there was a significant positive correlation between total physical activity and 25(OH)D level.Subgroup analysis showed that outdoor physical activity could significantly reduce the risk of vitamin D deficiency,but not for indoor physical activity;physical activity with high intensity could reduce the risk of vitamin D deficiency,but not for low physical activity;physical activity in different seasons could significantly reduce the risk of vitamin D deficiency.The result of experimental studies reports both acute exercise intervention and chronic exercise intervention could improve serum 25(OH)D level.Subgroup analysis showed that endurance training and endurance combined with resistance training could increase serum 25(OH)D level,but not for resistance training.Conclusion There is a significant positive correlation between physical activity and serum vitamin D level,and exercise intervention has a beneficial effect on the nutritional status of circulating vitamin D.

关 键 词：运动 身体活动 25-羟维生素D[25(OH)D] META分析 

分 类 号：G806[文化科学—运动人体科学]