3种药用菟丝子的生药学鉴别研究与数字化表征  

Study on pharmacognostic identification and digitization for the three medicinal seeds from the Cuscuta genus

作　　者：林锦锋[1] 葛蓉 康帅[2] 杨志业 谭颖仪 黄国凯[1] 马双成[2] LIN Jin-feng;GE Rong;KANG Shuai;YANG Zhi-ye;TAN Ying-yi;HUANG Guo-kai;MA Shuang-cheng(Guangdong Institute for Drug Control,NMPA Key Laboratory for Rapid Testing Technology of Drug,Guangzhou 510663,China;National Institutes for Food and Drug Control,NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine,Beijing 100050,China)

机构地区：[1]广东省药品检验所,国家药品监督管理局药品快速检验技术重点实验室,广州510663 [2]中国食品药品检定研究院,国家药品监督管理局中药质量研究与评价重点实验室,北京100050

出　　处：《药物分析杂志》2021年第8期1326-1334,共9页Chinese Journal of Pharmaceutical Analysis

基　　金：广东省省级科技计划项目(2018B020207008);重大新药创制——中药组分资源库及产业公共技术服务平台建设(2018ZX09735-006);青海省2018年科技基础条件平台项目——中藏药材数字化服务平台(2018-ZJ-T06)。

摘　　要：目的:对旋花科菟丝子属3种药用菟丝子商品进行生药学鉴别研究,建立性状和显微鉴定及其数字化表征规范,为菟丝子与其同属易混品及伪品的鉴别研究奠定基础。方法:借鉴植物学有关形态鉴定与分类的术语和研究方法,应用体式显微镜和光学显微镜等仪器设备及数码成像技术手段,从正面、侧面、腹面、表面等外观性状,横剖面和纵剖面特征,以及横切面和粉末的显微特征,对3种药用菟丝子商品进行比较鉴别和数字化表征,并将获得的数字化信息录入到数字标本平台。结果:明确了3种菟丝子外观形态、腹棱线、种脐等性状鉴别特征和种皮表皮细胞、种皮栅状细胞等显微鉴别特征,归纳总结了3种菟丝子的鉴别方法,为菟丝子类药材与混淆品的鉴定研究提供参考依据。结论:该鉴定方法简便环保、准确可靠,可作为3种菟丝子的鉴定依据。Objective:To explore the pharmacognostical identification study for the three medicinal seeds from the Cuscuta genus(Fam.Convolvulaceae),and to establish the standards of the macroscopic,microscopic identification and digital characterization for the authentication study of Cuscutae Semen and its adulterants.Methods:Referring to the terms and research methods of botanical morphological identification and classification,the comparative identification and digital characterization of three medicinal seeds from the Cuscuta genus were carried out by means of stereo microscope,optical microscope and digital imaging technology from the aspects of front,side,abdomen,surface appearance,cross section and longitudinal section characteristics,as well as the microscopic characteristics of cross section and powder.Then,the digital information was input to the digital specimen platform.Results:The macroscopic identification characters,such as the appearance,the ventral ridge,and the hilum,et al,and microscopic identification characters,such as the epidermis cell and the palisade cell of testa,of the medicinal seeds derived from Cuscuta australis R.Br.,Cuscuta chinensis Lam.,and Cuscuta japonica Choisy were clarified,and the identification methods were summarized,so as to provide reference for the identification of Cuscuta and its adulterants.Conclusion:The identification method is simple,environmental friendly,accurate and reliable,and can be used as the identification basis of the three medicinal seeds from the Cuscuta genus.

关 键 词：南方菟丝子 菟丝子 大菟丝子 生药学 性状鉴别 显微鉴别 数字化表征 

分 类 号：R917[医药卫生—药物分析学]