决明子及其易混淆品望江南的性状和显微鉴定与数字化研究  

Macroscopic and microscopic characters of Cassiae Semen and its adulterant Cassiae Occidentalis Semen and the digital study

作　　者：康帅[1] 江玲玲 罗婧 谢耀轩 张南平[1] 周碧乾 王冰 王铁杰 王淑红 马双成[1] KANG Shuai;JIANG Ling-ling;LUO Jing;XIE Yao-xuan;ZHANG Nan-ping;ZHOU Bi-qian;WANG Bing;WANG Tie-jie;WANG Shu-hong;MA Shuang-cheng(National Institutes for Food and Drug Control,NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine,Beijing 100050,China;Shenzhen Institute for Drug Control,NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine,Shenzhen 518057,China)

机构地区：[1]中国食品药品检定研究院,国家药品监督管理局中药质量研究与评价重点实验室,北京100050 [2]深圳市药品检验研究院,国家药品监督管理局中药质量研究与评价重点实验室,深圳518057

出　　处：《药物分析杂志》2021年第8期1352-1359,共8页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:探索决明子及其易混淆品望江南的生药学鉴定方法。方法:借鉴植物学有关形态鉴定与分类的术语和研究方法,应用体式显微镜和光学显微镜等仪器设备及数码成像技术手段,从正面、侧面、腹面、表面等外观性状,横剖面和纵剖面特征,以及横切面和粉末的显微特征,对2种药用决明子商品及易混淆品望江南进行比较鉴别和数字化表征。结果:2种药用决明子及易混淆品望江南在形状及剖面形状等形态特征上存在明显差异,在栅状细胞及草酸钙簇晶等粉末显微特征上存在着明显差异。结论:通过本次实验研究,归纳了2种药用决明子及望江南的生药学鉴定特征,可为决明子的监督检验、临床使用提供鉴定依据。Objective:To explore the pharmacognosic identification method for Cassiae Semen and its adulterant Cassiae Occidentalis Semen.Methods:Referring to the terms and research methods of botanical morphological identification and classification,using stereo microscopy and optical microscopy,in-depth study on the macroscopic and microscopic identification methods were performed for Cassiae Semen and its adulterant Cassiae Occidentalis Semen from the macroscopic identification characteristics,including the front view,lateral view,ventral view,surface view,transverse section view,longitudinal section view,and the microscopic identification characteristics,including the transverse section and the powder.Then the identification characters were summarized and digitized.Results:There were significant differences in the shape and profile of Cassia obtusifolia,Cassia tora and Cassia occidentalis,and microscopic identification characteristics in grid cells and calcium oxalate clusters between them.Conclusion:This study summarized the exclusive and practical features in pharmacognosic identification of Cassia obtusifolia,Cassia tora and Cassia occidentalis,providing a useful reference for supervision the clinical medication,inspection,and standard drafting.

关 键 词：钝叶决明 决明 望江南 生药学 性状鉴别 显微鉴别 数字化 

分 类 号：R917[医药卫生—药物分析学]