磁性石墨烯分散固相萃取结合液相色谱-串联质谱法测定水基胶中的双酚A和烷基酚  

Determination of bisphenol A and alkylphenol in water-based adhesives by magnetic graphene dispersion solid phase extraction combined with liquid chromatography-tandem mass spectrometry

作　　者：陈志燕[1] 邓惠敏[2] 王颖[2] 王维刚[1] 刘珊珊[2] 韦入丹 陈瑶[1] 纪元 唐纲岭[2] 孟冬玲[1] 杨飞[2] CHEN Zhiyan;DENG Huimin;WANG Ying;WANG Weigang;LIU Shanshan;WEI Rudan;CHEN Yao;JI Yuan;TANG Gangling;MENG Dongling;YANG Fei(Guangxi Tobacco Industiy Co.,Ltd.,Nanning 530001;China National Tobacco Quality Supervision&Test Center,Zhengzhou 450001)

机构地区：[1]广西中烟工业有限责任公司,南宁530001 [2]国家烟草质量监督检验中心,郑州450001

出　　处：《分析试验室》2021年第9期1094-1099,共6页Chinese Journal of Analysis Laboratory

摘　　要：建立了超高效液相色谱-串联质谱(UPLC-MS/MS)与磁性石墨烯相结合测定水基胶中双酚A、壬基酚和辛基酚的方法。样品提取后,以磁性石墨烯分散固相萃取净化,经BEH C_(18)色谱柱分离。分析物的回收率在81.5%~97.9%之间,日间相对标准偏差(RSDs)小于8.0%。所有化合物均获得了良好的线性系数(r≥0.9996),检出限(LOD)和定量限(LOQ)范围分别为3~8μg/kg和10~26μg/kg。采用该方法对20个水基胶实际样品进行检测,仅有1个样品检出4-正壬基酚。该方法可用于测定水基胶中双酚A和4种烷基酚的含量。An ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)method combined with magnetic graphene dispersive solid phase extraction for the determination of bisphenol A,nonylphenol and octylphenol in water-based adhesives was established.After extracted,the sample was purified by magnetic graphene dispersion solid phase extraction,and separated using a BEH C_(18)column.The recoveries were 81.5%-97.9%with the relative standard deviations(RSDs)less than 8.0%.Favourable coefficients(r≥0.9996)were achieved for all analytes.The LODs and LOQs for all analytes were 3-8μg/kg and 10-26μg/kg,respectively.Twenty actual samples were tested by this method,and the 4-n-nonylphenol was detected in only one sample.The results confirmed that this proposed method is capable of detecting the content of bisphenol A and four alkylphenols in water-based adhesives.

关 键 词：双酚A 壬基酚 辛基酚 水基胶 超高效液相色谱-串联质谱 

分 类 号：O657.63[理学—分析化学]