超声检查早孕期胎儿中枢神经系统畸形的临床分析  

Clinical analysis of ultrasonic examination of fetal central nervous system malformation in early pregnancy

作　　者：杨纯 张振显[2] 石海梅 高东梅[4] YANG Chun;ZHANG Zhenxian;SHI Haimei;GAO Dongmei(Medical College of Yanan University,Affiliated Hospital of Yanan University,Yan'An 716099,P.R.China;Department of CT,People's Hospital Clinic,Yan'An 717300,P.R.China;Ultrasound Room,Zichang People's Hospital,Yan'An 717300,P.R.China;Department of Pain Rehabilitation Medicine,Affiliated Hospital of Yan'an University,Yan'An 716000,P.R.China)

机构地区：[1]延安大学医学院延安大学医学院附属医院,陕西延安716099 [2]陕西省延安市人民医院CT诊断科,陕西延安717300 [3]陕西省子长市人民医院B超室,陕西延安717300 [4]延安大学附属医院疼痛康复医学科,陕西延安716000

出　　处：《医学影像学杂志》2021年第9期1475-1478,共4页Journal of Medical Imaging

摘　　要：目的探讨超声检查早孕期胎儿中枢神经系统(CNS)畸形的临床价值。方法选取我院1646例早孕期的孕妇进行超声检查,统计头胸部正中矢状断面、脊柱长轴断面、侧脑室水平横断面、小脑与颅后窝池断面显示情况。结果孕11~11+6周孕妇头胸部正中矢状断面、脊柱长轴断面、侧脑室水平横断面及小脑与颅后窝池断面的超声显示率分别为97.47%、98.31%、99.16%、98.73%,与孕12~12+6周(98.21%、98.88%、99.44%、98.44%)及孕13~13+6周(98.05%、99.03%、98.25%、98.64%)比较差异无统计学意义(P>0.05);早孕期超声检查的灵敏度为90.00%,特异性为100%,阳性预测值为100%,阴性预测值为99.94%。结论超声检查早孕期胎儿CNS畸形具有较高的显示率,为临床治疗提供依据。Objective To investigate the value of ultrasound in the diagnosis of fetal CNS malformation in early pregnancy.Methods 1646 cases of pregnant women in early pregnancy(11~13+6 weeks of gestation)were selected from September 2018 to September 2020.All pregnant women received ultrasound examination.The ultrasound findings of different sections(including head chest median sagittal section,spine long axis section,lateral ventricle horizontal section,cerebellum and posterior fossa cistern section)were analyzed.The ultrasound screening results of late pregnancy and the situation of CNS of pregnant women after induction of labor or birth were taken as the gold standard for diagnosis,and the sensitivity of ultrasound examination was calculated.Results There was no significant difference(P>0.05)between 12~12+6 weeks of gestation(98.21%,98.88%,99.44%,98.44%)and 13~13+6 weeks of gestation(98.05%,99.03%,98.25%,98.64%);The sensitivity,specificity,positive predictive value and negative predictive value of ultrasonography in early pregnancy were 90.00%(9/10),100.00%(1636/1636),100.00%(9/9)and 99.94%(1636/1637).Conclusion Early pregnancy(11~13+6 weeks of gestation)pregnant women using ultrasound has a high display rate;and the reasonable application of ultrasound in the diagnosis of fetal CNS malformation in early pregnancy has a significant effect,which can clearly diagnose the disease,with high clinical diagnosis rate,and can provide scientific basis for the follow-up reasonable treatment of CNS malformation fetus.

关 键 词：超声检查 早孕期 胎儿 中枢神经系统畸形 灵敏度 特异性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]