膝关节前交叉韧带断裂后单腿位置觉测试时脑电功率谱的变化特征  

Changes of electroencephalography power spectrum during joint position perception test after anterior cruciate ligament rupture

作　　者：苗欣[1] 黄红拾[1] 胡晓青[1] 时会娟 任爽[1] 敖英芳[1] MIAO Xin;HUANG Hong-shi;HU Xiao-qing;SHI Hui-juan;REN Shuang;AO Ying-fang(Department of Sports Medicine,Peking University Third Hospital,Institute of Sports Medicine of Peking University,Beijing Key Laboratory of Sports Injuries,Beijing 100191,China)

机构地区：[1]北京大学第三医院运动医学科,北京大学运动医学研究所,运动医学关节伤病北京市重点实验室,北京100191

出　　处：《北京大学学报（医学版）》2021年第5期871-876,共6页Journal of Peking University:Health Sciences

基　　金：国家自然科学基金(31900943);北京大学医学部教育教学研究(2020YB44);北京市自然科学基金(7202232)。

摘　　要：目的:同步记录膝关节前交叉韧带(anterior cruciate ligament,ACL)断裂患者进行单腿位置觉测试时的脑电信号,分析ACL断裂人群未伤侧、患侧分别运动时的脑电差异,明确ACL断裂造成的脑电功率谱变化特征,探究前交叉韧带断裂、膝关节失稳的中枢神经机制,为治疗及康复提供理论依据。方法:选择北京大学第三医院运动医学科2014年11月-2015年4月收治的一侧单纯ACL断裂男性患者16例参与研究,使用等速肌力测试设备进行单侧主动膝关节位置觉运动和被动膝关节位置觉运动。同步记录ACL断裂人群未伤侧和患侧被动膝关节位置觉测试、主动膝关节位置觉测试的脑电功率谱(electroencephalography,EEG),分析ACL断裂侧和非损伤侧单独运动时患者不同频段的脑电功率差异。主动膝关节位置觉任务和被动膝关节位置觉任务的目标位置为屈膝30°位。结果:ACL断裂人群未伤侧运动和患侧单独进行主动、被动膝关节位置觉测试发现,被动关节位置觉运动时,患侧较未伤侧脑电功率谱的Delta[F(1,15)=0.003,P=0.957,η_(P)^(2)=0.001]、Theta[F(1,15)=0.002,P=0.962,η_(P)^(2)<0.001]、Alpha[F(1,15)=0.002,P=0.966,η_(P)^(2)=0.001]、Beta[F(1,15)=0.008,P=0.929,η_(P)^(2)=0.001]波在Fz、Cz、Pz 3个脑区位置差异均无统计学意义;主动关节位置觉运动时,患侧脑电功率谱的Delta、Theta、Alpha、Beta波段在Fz和Pz电极点处显著高于未伤侧。结论:一侧ACL断裂带来的中枢变化,在进行对侧(未伤侧)被动运动时仍然存在;患侧主动运动时的脑电功率谱显著高于非伤侧。Objective:To measure the electroencephalography(EEG)of the patients with anterior cruciate ligament(ACL)rupture when performing joint position perception movement task,to compare the differences between the ACL rupture side and the unaffected side,to identify the EEG change in the power spectrum caused by the ACL rupture,and to provide evidence for the diagnosis,treatment and rehabi-litation for ACL injury as well as knee instability.Methods:Sixteen male patients,selected from the Department of Sports Medicine,Peking University Third Hospital from November 2014 to April 2015,with only ACL rupture on one side used isokinetic muscle strength testing equipment were enrolled in the study to perform unilateral active knee joint positional movement and passive knee joint positional movement tasks.EEG was recorded to compare between the affected and unaffected limb of ACL rupture patients when doing single leg movement tasks,including passive knee joint position test and active knee joint position sensation test.The target position of the active knee joint position movement task and the passive knee joint position movement task was 30 degrees of knee flexion.Results:During the passive knee joint position test,there was no significant difference in EEG power spectrum of Delta[F(1,15)=0.003,P=0.957,η_(P)^(2)=0.001],Theta[F(1,15)=0.002,P=0.962,η_(P)^(2)<0.001],Alpha[F(1,15)=0.002,P=0.966,η_(P)^(2)=0.001],Beta[F(1,15)=0.008,P=0.929,η_(P)^(2)=0.001]at Fz,Cz,and Pz between the affected and unaffected limbs in the ACL patients.During the active knee joint position movement task,the EEG power spectrum of Delta,Theta,Alpha,Beta at Fz and Cz location,on the affected side was significant higher than on the unaffected side.Conclusion:This study compared the differences between the ACL rupture side and the unaffected side during active knee position movement task and passive knee position movement task,and identifyied the EEG changes in the power spectrum caused by the ACL rupture,It was found that the central changes caused by

关 键 词：膝关节前交叉韧带 膝关节不稳 中枢神经 脑电功率谱 

分 类 号：R686[医药卫生—骨科学]