肺泡表面活性物质联合鼻塞持续气道正压通气对肺透明膜病早产儿血气指标的影响  

Impact of Pulmonary Surfactant Combined with Nasal Continuous Positive Airway Pressure Ventilation on Blood Gas Indicators of Premature Infants with Hyaline Membrane Disease

作　　者：莫志宇 梁波 卢兰花 MO Zhiyu;LIANG Bo;LU Lanhua(The Third People's Hospital of Longgang District,Shenzhen 518000,China)

机构地区：[1]深圳市龙岗区第三人民医院,广东深圳518000

出　　处：《临床医学工程》2021年第10期1323-1324,共2页Clinical Medicine & Engineering

基　　金：广东省中医药局科研项目(项目编号:20191277)。

摘　　要：目的探讨PS联合NCPAP治疗肺透明膜病(HMD)早产儿的效果以及对血气指标的影响。方法72例HMD早产儿随机分为两组各36例,对照组给予NCPAP治疗,观察组给予NCPAP+PS治疗,比较两组的血气指标、临床疗效、并发症。结果治疗24 h后,观察组的PaCO2、PaO2均显著优于对照组(P<0.05)。观察组的总有效率显著高于对照组,并发症发生率显著低于对照组(P<0.05)。结论NCPAP联合PS治疗早产儿HMD有助于提高疗效,改善血气指标,降低并发症发生率。Objective To explore the effect of PS combined with NCPAP in the treatment of premature infants with hyaline membrane disease(HMD)and the impact on blood gas indicators.Methods 72 premature infants with HMD were randomly divided into two groups,with 36 cases in each group.The control group was treated with NCPAP,while the observation group was treated with NCPAP+PS.The blood gas indicators,clinical efficacy and complications were compared between the two groups.Results After 24 h of treatment,the PaCO2 and PaO2 of the observation group were significantly better than those of the control group(P<0.05).The total effective rate of the observation group was significantly higher than that of the control group,and the incidence of complications was significantly lower than that of the control group(P<0.05).Conclusions PS combined with NCPAP in the treatment of premature infants with HMD can improve the efficacy,improve blood gas indicators and reduce the incidence of complications.

关 键 词：肺透明膜病 早产儿 肺泡表面活性物质 鼻塞持续气道正压通气 血气指标 

分 类 号：R722.6[医药卫生—儿科]