维生素D水平、人体骨密度与良性阵发性位置性眩晕的关系探讨  

Discussion on the Relationships of Vitamin D Level and Bone Mineral Density with Benign Paroxymoron Positional Vertigo

作　　者：张莉[1] 刘超[1] 许晓辉[1] 黄超[1] ZHANG Li;LIU Chao;XU Xiaohui;HUANG Chao(Department of Neurology,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471009,China)

机构地区：[1]郑州大学附属洛阳市中心医院神经内科,河南洛阳471009

出　　处：《临床医学工程》2021年第10期1331-1332,共2页Clinical Medicine & Engineering

基　　金：2018年度河南省医学科技攻关计划联合共建项目(项目编号:2018020907)。

摘　　要：目的探讨维生素D水平、人体骨密度与良性阵发性位置性眩晕(BPPV)的关系。方法选取120例BPPV患者作为观察组,120例健康体检者作为对照组,比较两组的血清25-(OH)2-VitD3水平和骨密度T值,并探讨二者与BPPV的关系。结果观察组的血清25-(OH)2-VitD3水平和骨密度T值均显著低于对照组(P<0.05)。观察组≥48岁女性的骨密度T值显著低于对照组(P<0.05)。多因素Logistic回归分析显示,25-(OH)2-VitD3水平和骨密度T值与BPPV的发生密切相关,25-(OH)2-VitD3水平和骨密度T值降低是引发BPPV的独立危险因素(P<0.05)。结论维生素D水平、人体骨密度与BPPV的发生密切相关,25-(OH)2-VitD3水平和骨密度T值越低,BPPV的发生率越高,≥48岁的绝经期女性BPPV患者更容易出现骨质疏松。Objective To explore the relationships of vitamin D level and bone mineral density with benign paroxymoron positional vertigo(BPPV).Methods 120 patients with BPPV were selected as the observation group,and 120 healthy individuals were selected as the control group.The serum 25-(OH)2-VitD3 level and bone mineral density T value were compared between the two groups,and the relationships of two indicators with with BPPV were discussed.Results The serum 25-(OH)2-VitD3 level and bone mineral density T value in the observation group were significantly lower than those in the control group(P<0.05).The bone mineral density T value of women≥48 years old in the observation group was significantly lower than that in the control group(P<0.05).Multivariate Logistic regression analysis showed that 25-(OH)2-VitD3 level and bone mineral density T value were closely related to the occurrence of BPPV,and decreased 25-(OH)2-VitD3 level and bone mineral density T value were independent risk factors for the occurrence of BPPV(P<0.05).Conclusions Vitamin D level and bone mineral density are closely related to the occurrence of BPPV.The lower the 25-(OH)2-VitD3 level and bone mineral density T value are,the higher the incidence of BPPV is.Menopausal women≥48 years old with BPPV are more prone to osteoporosis.

关 键 词：维生素D 人体骨密度 良性阵发性位置性眩晕 关系 

分 类 号：R441.2[医药卫生—诊断学]