仰卧位手法牵引对神经根型颈椎病患者血清炎症因子的影响  

Effect of supine manipulation traction on serum inflammatory cytokines in patients with cervical spondylotic radiculopathy

作　　者：马军廷[1] 张振国 袁燕[1] 姬生辉 MA Junting;ZHANG Zhenguo;YUAN Yan;JI Shenghui(Department of Rehabilitation Medicine,Liaocheng People's Hospital,Liaocheng,Shandong,China,252000)

机构地区：[1]聊城市人民医院康复医学科,山东聊城252000

出　　处：《分子诊断与治疗杂志》2021年第9期1486-1489,1493,共5页Journal of Molecular Diagnostics and Therapy

基　　金：山东省医药卫生科技发展计划面上项目(2018 HW032)。

摘　　要：目的观察仰卧位手法牵引治疗对神经根型颈椎病(CSR)患者血清炎症因子的影响。方法随机选取本院103例CSR患者为研究对象,按照随机数字表法分为观察组(n=52)和对照组(n=51),对照组给予药物及颈部按摩治疗,观察组在对照组基础上加以仰卧位手法牵引治疗。比较两组治疗前后颈椎功能、血清IL-1β、IL-8、NF-kB水平、症状体征改善及临床疗效。结果与治疗前相比,治疗4周及随访3个月后,两组视觉模拟评分法(VAS)、颈椎功能障碍指数评分量表(NDI)评分均显著降低,颈椎病疗效评定标准(JOA)评分均显著升高,两组临床症状评分均显著降低,且治疗后组间比较差异均有统计学意义(P<0.05)。治疗4周后,两组血清IL-1、IL-8、NF-κB水平均显著降低,差异均有统计学意义(P<0.05)。与治疗前相比,治疗4周及随访3个月后,两组临床症状评分均显著降低,且治疗后组间比较差异均有统计学意义(P<0.05)。观察组愈显率、总有效率均高于对照组,差异均有统计学意义(P<0.05)。结论仰卧位手法牵引治疗可明显改善CSR患者腰椎功能和症状体征,纠正血清炎症因子水平,具有一定的效果,值得推荐。Objective To observe the effect of manual traction therapy in supine position on serum inflammatory factors in patients with cervical spondylotic radiculopathy(CSR).Methods 103 CSR patients in the hospital were randomly selected as the research subjects,and they were divided into the observation group(n=52) and the control group(n=51) according to the random number table method.The control group was given drugs and neck massage,and the observation group applied supine manipulation traction on the basis of the control group.The cervical spine function,the levels of IL-1β,IL-8 and NF-κB,improvement status of symptoms and signs and clinical efficacy were compared between the two groups before and after treatment.Results After 4 weeks of treatment and 3 months of follow-up,the scores of visual analogue scale(VAS) and neck disability index(NDI) in the two groups were significantly reduced while the score of Japanese Orthopedic Association(JOA) was significantly increased,the scores of clinical symptoms were significantly reduced compared with before treatment,and the differences between the groups after treatment were statistically significant(P<0.05).After 4 weeks of treatment,the levels of serum IL-1,IL-8 and NF-kB in the two groups were significantly reduced,and the differences were statistically significant(P<0.05).Compared with before treatment,after 4 weeks of treatment and 3 months of follow-up,the clinical symptom scores of the two groups were significantly reduced,and the differences between the groups after treatment were statistically significant(P<0.05).The recovery rate and total effective rate of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Supine manipulation traction can significantly improve the lumbar function,symptoms and signs of CSR patients,and correct the levels of serum inflammatory factors in CSR patients CSR.It has a certain effect and is worth recommending.

关 键 词：神经根型颈椎病 颈椎功能 NDI评分 白介素-1Β 白介素-8 

分 类 号：R274.9[医药卫生—中西医结合]