结核性积液图文报告模式巨噬细胞比例与积液生化联合分析的临床意义  

作　　者：孙明月 吴茅[2] 王珍妮[2] 林慧君[2] 

机构地区：[1]浙江省德清县第三人民医院,313201 [2]浙江省人民医院,310014

出　　处：《浙江临床医学》2021年第9期1345-1346,1349,共3页Zhejiang Clinical Medical Journal

摘　　要：I目的探讨结核性装膜腔积液图文报告中巨噬细胞(Ma)比例与积液生化水平的相关性。方法选取2013年1月至2018年12月年经临床确诊的结核性浆膜腔积液211例为观察组,按图文报告巨噬细胞比例分低值、中值、高值三组,另取慢性非特异性炎症性积液86例为对照组,比较各组积液腺苷脱氨酶(ADA)、乳酸脫氫酶(LDH)、总蛋白(TP)、葡萄糖(GLU)水平。结果各结核组ADA、LDH、TP均明显高于对照组(P<0.01),而GLU均低于对照组,差异有统计学意义(P<0.01)。在结核组中,随巨噬细胞比例升高,ADA、LDH、TP呈逐渐降低趋势,其中高值组ADA低于低值组,差异有统计学意义(P<0.05);GLU随巨噬细胞比例升高缓慢上升。结论巨噬细胞比例联合积液生化检测与单-指标检测模式相比,能够提高诊断效能,有助于结核性积液的辅助诊断。Objective To provide the theoretical and experimental basis for the research of tuberculous efiusion graphic repont,the research explored the correlation between the ratio of macrophages(Ma)in graphic report of tuberculous serous cavity efusion and the levels of adenosine deaminase(ADA),lactate dehydrogenase(LDH),totl protein(TP)and glucose(GLU).Methods 211 clinical caces of tuberculous serous caviry efision from 2013 to 2018 were selected as the experimental group,and were divided into three groups(low raio,median rario and high ratio)according to the proportion of macrophage in the graphic report.In addition,86 clinical cases of chronic non-specific inflammatory efiusions were selced as the control group.The levels of ADA,LDH,TP and GLU in each group were stically analyzed.Results The levels of ADA,LDH and TP in each experimental group were signifcantly higher than those of the control group(P<0.01),while the level of GLU was significandly lower than the control group(P<0.01).In the experimental group,as the proportion of macrophage increased,the levels of ADA,LDH,TP showed gnadual downward trends,of which the level of ADA in the high-ratio group was signifcanly lower than that in the low--natio group(P<0.05);GLU increased slowly with the proportion of macrophage increasing.Conclusion Compared with the single index detection mode,this deection mode combined the ratio of macrophage with biochemical detection of efusion can improve the eficiency of tuberculous efusion diagnostic.

关 键 词：结核性积液 巨噬细胞 积液生化 

分 类 号：R52[医药卫生—内科学]