One-step viscoelastic agent technique for ICL V4c implantation for myopia  

作　　者：Hua-Mao Miao Feng Zhao Ling-Ling Niu Jing Zhao Xiao-Ying Wang Xing-Tao Zhou 

机构地区：[1]Department of Ophthalmology,Eye and ENT Hospital of Fudan University,NHC Key Laboratory of Myopia(Fudan University),Research Center of Ophthalmology and Optometry,Shanghai 200031,China [2]Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care(20DZ2255000),Shanghai 200031,China [3]Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China

出　　处：《International Journal of Ophthalmology(English edition)》2021年第9期1359-1364,共6页国际眼科杂志（英文版）

基　　金：the National Natural Science Foundation of China for Young Scholars(No.81700872);the National Natural Science Foundation of China(No.81770955);the Project of Shanghai Science and Technology(No.17411950200;No.20410710100);the Joint Research Project of New Frontier Technology in Municipal Hospitals(No.SHDC12018103);the Clinical Research Plan of SHDC(No.SHDC2020CR1043B);the Project of Shanghai Xuhui District Science and Technology(No.2020-015)。

摘　　要：AIM:To investigate the safety and efficacy of using a onestep viscoelastic agent technique for posterior chamber phakic implantable collamer lens with a central hole(ICL V4 c)implantation for myopia correction.METHODS:The one-step viscoelastic agent technique for ICL V4 c implantation was used in 100 eyes of 52 patients.Refractive outcomes,intraocular pressure(IOP),corneal endothelial cell,and corneal densitometry values were evaluated at 1 d,1 wk,1 and 3 mo postoperatively.RESULTS:All the surgeries were uneventful.No corrected distance visual acuity was lost after 3 mo.IOP was 16.12±3.18 mm Hg before surgery,and 14.74±3.08 mm Hg at 1d and 14.50±2.56 mm Hg at 3 mo after surgery(P<0.05).Corneal endothelial cell density was 2580±242 cell/mm^(2),the coefficient of variation in cell size was 42.11%±7.92%,and the percentage of hexagonal cells was 40.98%±9.46%before surgery.No significant difference was found when these outcomes were compared between the studied time points(P>0.05).The corneal densitometry values of the central 2 mm and 2 to 6 mm areas showed similar regularities.After surgery,the values significantly increased at 1 d,then decreased to the preoperative values at 1 wk,and then continued to decrease at 3 mo(P<0.05).CONCLUSION:The one-step viscoelastic agent technique for ICL V4c implantation is found to be safe and effective for myopia correction and causes little disturbance to the cornea.

关 键 词：phakic intraocular lens V4c viscoelastic agent MYOPIA intraocular pressure corneal endothelial cell corneal densitometry 

分 类 号：R779.6[医药卫生—眼科]