糖尿病合并尿路感染的临床特点及中医证型分布规律研究  

Study on the Clinical Characteristics and the Distribution of Traditional Chinese Medicine Syndrome Types in Diabetes Mellitus Complicated with Urinary Tract Infection

作　　者：曹玲 熊莉华[2] CAO Ling;XIONG Li-Hua(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;Dept.of Endocrinology,Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510120 Guangdong,China)

机构地区：[1]广州中医药大学第二临床医学院,广东广州510405 [2]广东省中医院内分泌科,广东广州510120

出　　处：《广州中医药大学学报》2021年第10期2067-2072,共6页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：【目的】探索糖尿病合并尿路感染的临床特点及中医证型分布规律,以期为糖尿病合并尿路感染的中医临床辨证施治提供客观依据。【方法】采用回顾性研究方法,选取2010年1月至2020年12月广东省中医院收治的明确诊断为糖尿病合并尿路感染的300例患者为研究对象,观察其不同性别、年龄的中医证型分布情况,以及糖尿病病程及空腹血糖(FBG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbAlc)水平与并发尿路感染的关系。【结果】(1)性别、年龄分布:糖尿病合并尿路感染患者中,以女性为主,占88.33%(265/300),而男性较少,仅占11.67%(35/300),差异有统计学意义(P<0.05);患者以60~70岁年龄段为主,其次为70~80岁和50~60岁年龄段,差异有统计学意义(P<0.05)。(2)中医证型分布:以肝肾阴虚夹痰瘀证为主,占87.67%(263/300),与非肝肾阴虚夹痰瘀证比较,差异有统计学意义(P<0.05)。(3)不同性别、年龄段的中医证型分布:不论男性还是女性,均以肝肾阴虚夹痰瘀证为主;湿热互结证主要集中于40~50岁,肝肾阴虚夹痰瘀证和气阴两虚证主要集中于60~70岁,阴阳两虚证主要集中于80岁以上患者;不同性别、年龄的中医证型分布情况比较,差异均有统计学意义(P<0.05)。(4)糖尿病病程≥120个月(10年)以及发病期间FBG≥7 mmol/L、2hPG≥10 mmol/L、HbAlc≥7%的患者,并发尿路感染的机率明显增加,差异均有统计学意义(P<0.05)。【结论】糖尿病合并尿路感染多发生在中老年人,以女性为多见,肝肾阴虚夹痰瘀证是其最常见证型,且不同性别、年龄段的中医证型分布有所不同;糖尿病合并尿路感染的发生与糖尿病病程及FBG、2hPG、HbAlc水平有关。Objective To explore the clinical characteristics and the distribution of traditional Chinese medicine(TCM)syndrome types in diabetes mellitus(DM)complicated with urinary tract infection,so as to provide an objective basis for the TCM clinical diagnosis and treatment of DM complicated with urinary tract infection.Methods A retrospective study was carried out in 300 DM patients complicated with urinary tract infection who were admitted to Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2010 to December 2020.We observed the distribution of TCM syndromes in the patients with different genders and age groups,and examined the correlation of incidence of urinary tract infection with the course of DM as well as the levels of fasting blood glucose(FBG),2-hour postprandial blood glucose(2hPG),and glycosylated hemoglobin(HbAlc).Results(1)Distribution of the gender and age groups:DM patients complicated with urinary tract infection were predominated by the female(88.33%,265/300),and only 11.67%(35/300)were the male.The difference in the gender was statistically significant(P<0.05).Most of the patients were aged between 60 and 70 years old,following by the age group of 70~80 years old and age group of 50~60 years old,the difference in the age group being statistically significant(P<0.05).(2)The distribution of TCM syndrome types:the primary syndrome was liver-kidney yin deficiency complicated with phlegm and stasis,accounting for 87.67%(263/300),which differed from that of the non-liver-kidney yin deficiency complicated with phlegm and stasis syndrome(P<0.05).(3)The distribution of TCM syndromes in patients with different genders and age groups:both of the male and female patients were characterized by liver-kidney yin deficiency with phlegm and stasis syndrome.The syndrome of dampness blended with heat was commonly seen in the patients aged 40~50,the syndrome of liver-kidney yin deficiency complicated with phlegm and blood stasis and the syndrome of qi and yin deficiency were commonly seen in the

关 键 词：糖尿病 尿路感染 临床特点 中医证型 肝肾阴虚夹痰瘀证 

分 类 号：R259.871[医药卫生—中西医结合]