基于ICP-MS技术的两种基原阴地蕨药材无机元素差异研究  

Study on the differences of elements between Botrychium ternatum (Thunb.) Sw. and Botrychium lanuginosum Wall. based on ICP-MS technique

作　　者：闻焜 代欣桃 杜泽飞 李文锐 杨子秋 段宝忠 WEN Kun;DAI Xintao;DU Zefei;LI Wenrui;YANG Ziqiu;DUAN Baozhong(College of Pharmaceutical Science,Dali University,Dali 671000,China;Dali Institute For Food and Drug Control,Dali 671000,China;Dali Institute for Food Control,Dali 671000,China)

机构地区：[1]大理大学药学院,云南大理671000 [2]大理州食品药品检验所,云南大理671000 [3]大理州食品检验检测院,云南大理671000

出　　处：《沈阳药科大学学报》2021年第8期809-814,共6页Journal of Shenyang Pharmaceutical University

基　　金：南省重大科技专项(202002AA100007);云南省万人“青年拔尖人才”计划;大理大学创新团队项目(ZKLX2019318);云南省专家工作站(2021-1)。

摘　　要：目的探讨阴地蕨不同基原的无机元素特征,为其开发利用提供科学参考。方法采用ICP-MS法测定20种无机元素含量,同时结合聚类分析和主成分分析方法对其无机元素特征进行研究。结果两种基原药材无机元素指纹特征图谱差异明显,基于无机元素含量的HCA和PCA分析显示,两个物种可明显区分。结论本研究建立的方法可用于阴地蕨药材无机元素的含量测定;基于无机元素特征结合HCA和PCA的分析模型,可用于阴地蕨不同基原药材的快速鉴别。Objective To explore the characteristics of inorganic elements in different originals of Herba Botrychii, and to provide scientific reference for its development and utilization.Methods The contents of 20 inorganic elements were determined by ICP-MS,and the characteristics of inorganic elements were studied by hierarchical cluster analysis(HCA) and principal component(PCA) analysis.Results There were significant differences in the fingerprint of inorganic elements between the two species.The results showed that the two species could be differentiate by HCA and PCA analysis.Conclusion The method was a fast, accurate and reliable, and can be used for determination of inorganic elements of Herba Botrychii.and the inorganic element determination combined with HCA and PCA analysis could be used to identification of different species of Herba Botrychii.

关 键 词：阴地蕨 无机元素 电感耦合等离子体质谱 聚类分析 主成分分析 

分 类 号：R917[医药卫生—药物分析学]