归芪退热汤治疗气虚血亏型癌性发热临床观察  

Clinical Observation on Guiqi Tuire Decoction in the Treatment of Cancerous Fever Cased by Deficiency of both Qi and Blood Type

作　　者：于红伟 乔元勋 YU Hongwei;QIAO Yuanxun(Graduate School,Shandong University of Traditional Chinese Medicine,Shandong Province,Jinan 250355,China;Department of Hematology,Tai’an Hospital of Traditional Chinese Medicine,Shandong Province,Tai’an 271200,China)

机构地区：[1]山东中医药大学研究生院,山东济南250355 [2]泰安市中医医院肿瘤血液科,山东泰安271200

出　　处：《中国中医药现代远程教育》2021年第18期87-90,共4页Chinese Medicine Modern Distance Education of China

摘　　要：目的观察归芪退热汤治疗气虚血亏型癌性发热的临床疗效。方法选取2018年10月—2019年7月泰安市中医医院收治的64例癌性发热患者,按随机数字表法分为观察组和对照组,每组32例。对照组给予吲哚美辛栓纳肛治疗,观察组在对照组基础上予以中药归芪退热汤口服,2组均以7 d为1个疗程。比较2组的退热疗效、吲哚美辛栓平均使用次数、中医证候疗效指数、Karnofsky功能状态(Karnofsky performance status,KPS)评分及不良反应总发生率。结果观察组的退热总有效率为87.5%(28/32),高于对照组的62.5%(20/32),差异有统计学意义(P <0.05);观察组的吲哚美辛栓使用(6.22±0.61)次,低于对照组的(8.19±0.86)次,差异有统计学意义(P <0.05);观察组的中医证候疗效指数优于对照组,差异有统计学意义(P <0.05);观察组治疗后的KPS评分高于对照组,差异有统计学意义(P <0.05);观察组的不良反应总发生率低于对照组,差异有统计学意义(P <0.05)。结论气虚血亏型癌性发热患者经服用归芪退热汤治疗,能提高患者的治疗效果,减少吲哚美辛栓的使用次数,减少不良反应的发生,值得临床应用推广。Objective To observe the clinical therapeutic effect of Guiqi Tuire decoction on cancerous fever caused by qi-blood deficiency. Methods A total of 64 patients with cancerous fever admitted to Tai’an Hospital of Traditional Chinese Medicine from October2018 to July 2019 were selected. All patients were randomly divided into two groups according to the random number table method.The control group was treated with indomethacin suppository, and the observation group received Guiqi Tuire decoction on the basis of it. The two groups were treated with 7 days as a course of treatment. The changes in body temperature, the number of indomethacin suppositories, the KPS score, and the improvement of TCM symptoms were compared. Results The total effective rate in the observation group was 87.5%(28/32), which was higher than that in the control group(62.5%(20/32)), and the difference was statistically significant(P <0.05). Indomethacin suppositories were used(6.22± 0.61) times in the observation group, which was lower than that in the control group(8.19± 0.86) times, and the difference was statistically significant(P <0.05). The TCM syndrome efficacy index of the observation group was better than that of the control group, and the difference was statistically significant(P <0.05). The KPS score of the observation group was higher than that of the control group, and the difference was statistically significant(P <0.05). The total incidence of adr in the observation group was lower than that in the control group, and the difference was statistically significant(P<0.05).Conclusion Guiqi Tuire decoction has a significant clinical effect. At the same time, it can improve the clinical symptoms and improve the quality of life of patients.

关 键 词：归芪退热汤 气虚血亏 癌性发热 生活质量 甘温除热 

分 类 号：R273[医药卫生—中西医结合]