基于“心-脑-肠轴”理论概述肠道菌群与难治性高血压的发病  

Review of gut flora and the pathogenesis of resistant hypertension based on the theory of‘heart-brain-gut axis’

作　　者：黄宏 肖珉[2] 邹冲[1] 方祝元[1] HUANG Hong;XIAO Min;ZOU Chong;FANG Zhu-yuan(Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)

机构地区：[1]南京中医药大学附属医院,南京210029 [2]北京中医药大学东直门医院,北京100700

出　　处：《中华中医药杂志》2021年第8期4809-4811,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点研发计划(No.2018YFC1704900,No.2018YFC1704400)。

摘　　要：肠道菌群失调是难治性高血压发病的重要因素之一,中医“心”“脑”“肠”生理病理上相互联系,共同构成“心-脑-肠轴”理论体系,与现代医学有关神经系统异常导致肠道菌群失调进而诱发心血管系统疾病相似,因此,通过中医“心-脑-肠轴”理论探索现代医学有关肠道菌群与难治性高血压的作用机制及治疗方法是中西医结合治疗难治性高血压的新方向,有利于提高难治性高血压与肠道微生物相互作用的新认识,从而为科学研究提供理论基础。The imbalance of gut flora is one of the important factors in the pathogenesis of resistant hypertension.In traditional Chinese medicine,‘heart’,‘brain’and‘gut’are related to each other in physiology and pathology to form the theoretical system of‘heart-brain-gut axis’.Similar to modern medicine,abnormal nervous system leads to intestinal gut disorders and cardiovascular diseases.Therefore,exploring the mechanism and treatment of intestinal gut and resistant hypertension in modern medicine through the‘heart-brain-gut axis’theory of traditional Chinese medicine is a new direction of integrated traditional Chinese and Western medicine in the treatment of resistant hypertension.It is helpful to improve the new understanding of the interaction between resistant hypertension and intestinal microorganisms,so as to provide a theoretical basis for scientific research.

关 键 词：肠道菌群 心-脑-肠轴 难治性高血压 中西医结合 

分 类 号：R259[医药卫生—中西医结合]