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作 者:张哲 吕丹丹 魏延 韩伟 赵曙光 赵丽 ZHANG Zhe;LV Dandan;WEI Yan;HAN Wei;ZHAO Shuguang;ZHAO Li(Department of Gastroenterology,Tangdu Hospital,Air Force Military Medical University,Xi′an 710038,China)
机构地区:[1]空军军医大学唐都医院消化内科,陕西西安710038
出 处:《延安大学学报(医学科学版)》2021年第3期20-23,共4页Journal of Yan'an University:Medical Science Edition
基 金:国家自然科学基金(81270485)。
摘 要:目的观察超短波辅助治疗重症急性胰腺炎(severe acute pancreabibis,SAP)的临床疗效。方法收集空军军医大学唐都医院消化内科2017年1月至2019年12月收治入院的80例SAP患者,按治疗方式不同分为观察组与对照组,每组40例。对照组采用常规治疗,观察组在对照组治疗基础上附加超短波局部辅助治疗,观察两组患者血清C反应蛋白(CRP)、白细胞介素6(IL-6)、二胺氧化酶(DAO)、D-乳酸、细菌内毒素(LPS)的水平,记录并比较首次排气排便时间、住院天数及住院费用。结果观察组CRP、IL-6、DAO、D-乳酸、LPS表达及首次排气排便时间、住院天数、住院费用明显低于对照组,差异具有统计学意义(P<0.05)。结论超短波辅助治疗可有效降低SAP患者的炎症反应,改善肠道功能,减少住院天数,降低住院费用,具有临床推广意义。Objective To observe the clinical effect of ultrashort wave in the treatment of severe acute pancreatitis(SAP).Methods A total of 80 SAP patients admitted to the department of gastroenterology of Tangdu Hospital,Air Force Military Medical University from January 2017 to December 2019 were collected and divided into observation group and control group according to different treatment methods with 40 cases in each group.The control group received conventional treatment,the observation group added ultrashort wave local adjuvant therapy to the control group,and observed the serum C-reactive protein(CRP),interleukin 6(IL-6),diamine oxidase(DAO).The level of D-lactic acid and bacterial endotoxin(LPS)was recorded and compared with the time of the first exhaust defecation,the length of hospital stay and the cost of hospitalization.Results The observation group′s CRP,IL-6,DAO,D-lactic acid,LPS level,time to first defecation,length of hospital stay,and hospitalization cost were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions Ultrashort wave adjuvant therapy can effectively reduce the inflammatory response of SAP patients,improve intestinal function,reduce the number of hospital stays,reduce hospitalization costs,and has clinical significance.
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