不同煎煮方法对八味地黄汤药效的影响  

Effects of Different Decocting Methods on the Efficacy of Bawei Dihuang Decoction

作　　者：杨宏玲 吴振囯 张炜 查道成[4] YANG Hongling;WU Zhenguo;ZHANG Wei;ZHA Daocheng(Department of Traditional Chinese Medicine,Qiliyuan Township Hospital,Wolong District,Henan Nanyang 473009,China;Graduate School of Henan University of Traditional Chinese Medicine,Henan Zhengzhou 450008,China;Zhang Zhongjing Hospital,Henan Nanyang 473007,China;Nanyang Medical College,Henan Nanyang 473061,China)

机构地区：[1]河南省南阳市卧龙区七里园乡卫生院,河南南阳473009 [2]河南中医药大学研究生院,河南郑州450008 [3]河南省南阳张仲景医院,河南南阳473007 [4]南阳医学高等专科学校,河南南阳473061

出　　处：《中医药临床杂志》2021年第9期1760-1762,共3页Clinical Journal of Traditional Chinese Medicine

基　　金：河南省中医药青苗人才培养项目【No.豫中医科教(2018)16号】。

摘　　要：目的:观察不同煎煮方法对八味地黄汤药效的影响。方法:以八味地黄汤作为研究药物模型,将煎药机自动煎药方法设为对照组,将根据方剂中药材特性进行正规化煎煮设为观察组。观察两种不同煎煮方法总浸出物量、丹皮酚含量、煎出率及RSD情况。结果:观察组总浸出物量160g、丹皮酚含量0.021g/L,煎出率11.58%及RSD2.38%均高于对照组总浸出物量145g、丹皮酚含量0.012g/L、煎出率10.28%及RSD2.14%。结论:根据方剂中药材特性进行正规化煎煮较煎药机自动煎药可有效提高八味地黄汤药质量,提取药物有效成分,充分发挥药效。Objective To observe the effect of different decocting methods on the efficacy of Bawei Dihuang Decoction.Methods Bawei Dihuang Decoction was used as the drug model,the automatic decocting method of decocting machine was set as the control group,and the regularization decocting according to the characteristics of Chinese medicinal materials was set as the observation group.The total extract content,paeonol content,decocting rate and RSD of two different decocting methods were observed.Results The total extract content of 160g,paeonol content of 0.021g/L,decoctions rate of 11.58% and RSD2.38% in the observation group were higher than those in the control group,which were 145g,0.012g/L,decoctions rate of 10.28% and RSD2.14%.Conclusion Compared with automatic decocting machine,regular decocting according to the characteristics of traditional Chinese medicinal materials can effectively improve the quality of Bawei Dihuang Decoction,extract the effective ingredients and give full play to the drug effect.

关 键 词：八味地黄汤 煎药机自动煎药 中药材特性正规化煎煮 丹皮酚 

分 类 号：R28[医药卫生—中药学]