清虚汤加减治疗脊柱术后阴虚发热的疗效观察  

Observation of Curative Effect of Qingxu Decoction on Yin Deficiency Fever after Spinal Surgery

作　　者：孔赏 卢汪钰 李俊毅 马虎升 吴晓阳 吕振超 KONG Shang;LU Wangyu;LI Junyi;MA Husheng;WU Xiaoyang;LV Zhenchao(Henan University of Traditional Chinese Medicine,Henan Zhengzhou 450000,China;Henan Orthopedic Hospital,Henan Zhengzhou 450000,China)

机构地区：[1]河南中医药大学,河南郑州450000 [2]河南省骨科医院,河南郑州450000

出　　处：《中医药临床杂志》2021年第9期1786-1790,共5页Clinical Journal of Traditional Chinese Medicine

摘　　要：目的:观察清虚汤加减治疗脊柱术后阴虚发热的临床效果。方法:将符合标准的60例脊柱术后发热患者,按照入组顺序编号采用随机数表法随机分组,对照组患者采用双氯芬酸钠缓释胶囊治疗,观察组患者予以清虚汤加减治疗,比较2组血红蛋白及白蛋白第1天、第6天变化情况,首次用药后 1h体温下降度数及退热持续时间,治疗前及治疗后第1、第3、第5天体温变化情况,治疗后中医临床疗效评分。结果:观察组患者血红蛋白及白蛋白较对照组高,差异有统计学意义(P<0.05)。观察组患者治疗后1h体温下降度数低于对照组,而退热持续时间长于对照组(P<0.05),治疗前后不同时间点体温测量采用重复测量方差分析,治疗前后不同时间之间有显著差异(F=59.523,P<0.05);观察组治疗前体温最高,治疗第一天后降温最快,对照组治疗前体温较高,治疗第一天较第三天、第五天体温下降速度快,且观察组降温优于对照组(F=5.870,P=0.003);从时间点来看,治疗前2组体温未见明显差异(t=0.437,P=0.664),其余时间点观察组体温较低;治疗和时间存在交互效应(F=2.525,P=0.067)。观察组治疗后临床有效率总有效率达93.3%明显高于对照组 83.3%,差异有统计学意义(P<0.05)。结论:清虚汤加减治疗脊柱术后阴虚发热较双氯芬酸钠缓释胶囊作用时间长、临床效果好。Objective:To observe the clinical effect of Qingxu Decoction in treating yin deficiency fever after spinal surgery.Methods:Sixty patients with fever after spinal surgery that meet the criteria were randomly divided into groups according to the entry sequence number using a random number table method.The control group was treated with diclofenac sodium sustained-release capsules,and the observation group was treated with Qingxu Decoction.Comparison 2 Group hemoglobin and albumin changes on the 1st and 6th day,the degree of body temperature drop and the duration of antipyretic 1h after the first medication,the body temperature changes before and after the treatment on the 1,3,and 5 days,and the TCM clinic after treatment Efficacy score.Results:The hemoglobin and albumin of the observation group were higher than those of the control group,and the difference was statistically significant (P<0.05).The degree of body temperature decrease in the observation group 1h after treatment was lower than that of the control group,while the duration of antipyretics was longer than that of the control group (P<0.05).The body temperature measurement at different time points before and after treatment used repeated measurement analysis of variance,and there were significant differences between different times before and after treatment.(F=59.523,P<0.05);the observation group had the highest body temperature before treatment,and the fastest cooling rate after the first day of treatment.The control group had a higher body temperature before treatment,and the body temperature dropped faster on the first day of treatment than on the third and fifth days.And the observation group was better than the control group in cooling (F=5.870,P=0.003);from the time point of view,there was no significant difference in body temperature between the two groups before treatment (t=0.437,P=0.664),and the observation group’s body temperature was higher at other time points Low;there is an interactive effect between treatment and time (F=2.525,P=0.067)

关 键 词：清虚汤 脊柱术后 非感染性发热 

分 类 号：R255.1[医药卫生—中医内科学]