悬钩子属酚酸类成分及其生物活性研究进展  

Research Progress on Phenolic Acids and Their Biological Activities in Rubus

作　　者：王建雄 肖小武 王栋 陈丽楠 王兰欣 付辉政 WANG Jianxiong;XIAO Xiaowu;WANG Dong;CHEN Li'nan;WANG Lanxin;FU Huizheng(Jiangxi Institute for Drug Control,NMPA Key Laboratory of Quality Evaluation of Traditional Chinese Patent Medicine,Jiangxi Provincial Engineering Research Center of Drug and Medical Device Quality,Nanchang Jiangxi 330029,China;Jiangxi University of Traditional Chinese Medicine,Nanchang Jiangxi 330004,China;Jiangxi General Institute of Inspection,Testing and Certification,Nanchang Jiangxi 330052,China)

机构地区：[1]江西省药品检验检测研究院,国家药品监督管理局中成药质量评价重点实验室,江西省药品与医疗器械质量工程技术研究中心,江西南昌330029 [2]江西中医药大学,江西南昌330004 [3]江西省检验检测认证总院,江西南昌330052

出　　处：《药品评价》2021年第16期965-969,共5页Drug Evaluation

基　　金：江西省自然科学基金(20192BAB205115)。

摘　　要：悬钩子属为蔷薇科植物,在全国范围内分布极其广泛,其中大部分都含有酚酸类成分,例如:山楂,山莓,茅莓等。酚酸类成分在悬钩子属中是一种重要的活性成分,并且具有广泛的生物活性,包括抗肿瘤、抗氧化、抗炎抗菌和保肝等作用。本文对悬钩子属中酚酸类成分及其生物活性研究进展进行综述,为悬钩子属植物的进一步研究、提升药用价值及开发利用提供参考。Rubus belongs to Rosaceae,which is widely distributed in China,and most of them contain phenolic acids,such as hawthorn,strawberry,raspberry and so on.Phenolic acids are important active ingredients in Rubus,and have a wide range of biological activities,including anti-tumor,anti-oxidation,anti-bacterial and liver protection.In this paper,the research progress of phenolic acids and their biological activities in Rubus was described,in order to provide reference for further research,promotion of medicinal value and development and utilization of Rubus.

关 键 词：悬钩子属 药理作用 酚酸类 抗代谢药 抗肿瘤 生物活性 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]