流式细胞仪检测慢性乙型肝炎患者T淋巴细胞亚群的意义分析  

Analysis of the Significance of Flow Cytometry in Detecting T Lymphocyte Subsets in Patients with Chronic Hepatitis B

作　　者：柳国强 LIU Guo-qiang(Yingkou Economic and Technological Development Zone Central Hospital(The Sixth People's Hospital of Yingkou City),Liaoning Yingkou 115007)

机构地区：[1]营口经济技术开发区中心医院(营口市第六人民医院),辽宁营口115007

出　　处：《中国医疗器械信息》2021年第18期53-53,101,共2页China Medical Device Information

摘　　要：目的:探讨流式细胞仪检测慢性乙型肝炎患者T淋巴细胞亚群的意义。方法:2017年8月~2019年8月选择本院收治的慢性乙型肝炎患者51例作为观察组,健康体检者51例作为对照组,均采用流式细胞仪检测T淋巴细胞亚群,组间比较检测结果。结果:两组CD3+比较无统计学意义,P>0.05;观察组CD4+及CD4+/CD8+显著低于对照组,CD8+显著高于对照组,P<0.05。结论:针对慢性乙型肝炎患者采用流式细胞仪检测,明确T淋巴细胞亚群变化,可判断患者多伴随免疫功能低下,应重视免疫改善治疗,促使病情康复,诊治价值较高。Objective:To investigate the significance of flow cytometry in detecting T lymphocyte subsets in patients with chronic hepatitis B.Methods:From August 2017 to August 2019,51 patients with chronic hepatitis B in our hospital were selected as observation group and 51 patients with healthy physical examination as control group.All T lymphocyte subsets were detected by flow cytometry.Compare test results between groups.Results:The comparison of CD3+between the two groups was not statistically significant,P>0.05;CD4+and CD4+/CD8+in the observation group were significantly lower than those in the control group,and CD8+was significantly higher than the control group,P<0.05.Conclusion:For patients with chronic hepatitis B,flow cytometry is used to determine the changes of T lymphocyte subsets,which can be judged that patients are often accompanied by low immune function.Immunity improvement treatment should be emphasized to promote the recovery of the disease,and the diagnosis and treatment value is high.

关 键 词：流式细胞仪 慢性乙型肝炎 T淋巴细胞亚群 

分 类 号：R512.6[医药卫生—内科学]