雅培i2000化学发光分析仪检测HCV抗体的假阳性研究  

False Positive Study on Detection of HCV Antibody by Abbott i2000 Chemiluminescence Analyzer

作　　者：王镱达 WANG Yi-da(Liaoyang Central Hospital,Liaoning Liaoyang 111000)

机构地区：[1]辽阳市中心医院,辽宁辽阳111000

出　　处：《中国医疗器械信息》2021年第18期70-71,共2页China Medical Device Information

摘　　要：目的:研究分析雅培i2000化学发光分析仪检测HCV抗体的假阳性情况。方法:选取2019年12月~2020年12月在本中心采用雅培i2000化学发光分析仪进行HCV抗体检测的14532例患者为研究对象,通过分析仪筛查出阳性患者后,所有阳性患者均经HCV-RNA确诊,比较分析患者的检测结果。结果:14532例检测患者中阳性患者102例,阳性检出率为0.7%。102例阳性患者经HCV-RNA确诊后,阳性83例,阴性19例,假阳性率为18.6%,两种检测方法的阳性率存在明显差异(P<0.05)。结论:雅培i2000化学发光分析仪检测HCV抗体,虽然可检出阳性患者,但假阳性率比较高,临床应谨慎应用,在筛查出阳性患者后及时采用HCV-RNA确诊,提高检出准确率。Objective:To study and analyze the false positives of Abbott i2000 chemiluminescence analyzer in the detection of HCV antibodies.Methods:From December 2019 to December 2020,14532 patients who used Abbott i2000 chemiluminescence analyzer for HCV antibody detection in our center were selected as the research object.After the positive patients were screened by the analyzer,all positive patients were tested for HCV-RNA To confirm the diagnosis,compare and analyze the patient’s test results.Results:Among the 14532 detected patients,102 were positive patients,and the positive detection rate was 0.7%.After 102 positive patients were diagnosed by HCV-RNA,83 were positive and 19 were negative.The false positive rate was 18.6%.There was a significant difference in the positive rate of the two detection methods(P<0.05).Conclusion:Abbott i2000 chemiluminescence analyzer detects HCV antibodies.Although positive patients can be detected,the false positive rate is relatively high.It should be used with caution in clinical practice.HCV-RNA should be used to confirm the diagnosis in time after positive patients are screened to improve the detection accuracy.

关 键 词：雅培 i2000化学发光分析仪 HCV抗体 阳性 HCV-RNA 

分 类 号：R446.1[医药卫生—诊断学]