猫抓病合并吉兰-巴雷综合征1例报告并文献复习  

Cat-scratch disease combined with Guillain-Barré syndrome: a case report and literature review

作　　者：段纯 全斌[1] 袁荆 王妮[1] 喻艳林[1] 侯为顺[1] DUAN Chun;QUAN Bin;YUAN Jing;WANG Ni;YU Yan-lin;HOU Wei-shun(Department of Infectious Diseases,Yijishan Hospital of Wannan Medical College,Wuhu 241000,China;Department of Critical Care Medicine,Yijishan Hospital of Wannan Medical College,Wuhu 241000,China)

机构地区：[1]皖南医学院弋矶山医院感染性疾病科,安徽芜湖241000 [2]皖南医学院弋矶山医院重症医学科,安徽芜湖241000

出　　处：《中国感染控制杂志》2021年第10期938-942,共5页Chinese Journal of Infection Control

摘　　要：猫抓病是由汉塞巴尔通体侵入人体后引起的一种感染性疾病,其临床表现多样,出现神经学表现者较为罕见,容易误诊。某院收治1例以"右侧腹股沟包块渐进性增大10 d,四肢麻木无力2 d"入院的45岁男性,病程中患者出现发热、右侧腹股沟淋巴结肿大、双下肢对称性瘫痪、感觉障碍,脑脊液检查示蛋白-细胞分离特征,诊断为吉兰-巴雷综合征,后经病理检查、既往猫抓咬史及宏基因组二代测序检出汉塞巴尔通体,最终确诊猫抓病。本文就该例猫抓病合并吉兰-巴雷综合征病例进行报告及文献复习,旨在提高临床对猫抓病的认识。Cat-scratch disease(CSD)is an infectious disease caused by the invasion of Bartonella henselae into the human body,its clinical manifestations are varied,and neurological manifestations are relatively rare,which is easy to be misdiagnosed.A 45-year-old male was admitted to a hospital with“right groin mass gradually increased for 10 days,limb numbness and weakness for 2 days”.During the course of disease,patient developed fever,enlarged right inguinal lymph nodes,symmetrical paralysis of both lower extremities and sensory disturbance,cerebrospinal fluid examination showed protein-cell separation characteristics,which was diagnosed with Guillain-Barrésyndrome(GBS),through pathologic examination,previous cat-scratch history and detection of Bartonella henselae by meta-genomic next-generation sequencing,diagnosis of CSD was finally confirmed.In this paper,a case of CSD complicated with GBS was reported and literature review was conducted,so as to improve the clinical understanding on cat-scratch disease.

关 键 词：猫抓病 吉兰-巴雷综合征 汉塞巴尔通体 

分 类 号：R516[医药卫生—内科学]