温阳通络法辅助治疗难治性高血压的近期疗效观察  

Observation on the Short-term Therapeutic Effect of Wenyang Tongluo method in the Treatment of Refractory Hypertension

作　　者：王婵[1] 王卓 邢潇萌 WANG Chan;WANG Zhuo;XING Xiaomeng(Tianjin Third Central Hospital Branch,Tianjin 300250,China)

机构地区：[1]天津市第三中心医院分院,天津300250

出　　处：《中医药临床杂志》2021年第8期1513-1516,共4页Clinical Journal of Traditional Chinese Medicine

摘　　要：目的:观察温阳通络法辅助治疗难治性高血压的疗效。方法:选取符合标准的78例顽固性高血压患者为研究对象,随机分为观察组(n=39)和对照组(n=39)。2组患者均予以苯磺酸氨氯地平+厄贝沙坦氢氯噻嗪片口服,配合低盐低脂饮食、戒烟酒、改善生活方式等措施。对照组予以通心络胶囊口服治疗,观察组以温阳通络为法,予以通心络胶囊加中药配方颗粒治疗,2组治疗时间均为12周。比较2组近期疗效、中医证候积分(头晕、头痛、心悸、舌象)、血压水平、血压达标情况及不良反应。结果:观察组中医证候疗效总有效率明显高于对照组(P<0.05)。2组治疗后头晕、头痛、心悸、舌象评分较治疗前明显下降,且观察组治疗后头晕、头痛、心悸、舌象评分明显低于对照组(P<0.05)。2组治疗后收缩压、舒张压较治疗前明显下降,观察组治疗后收缩压、舒张压明显低于对照组(P<0.05)。观察组血压达标总有效率明显高于对照组(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:对难治性高血压患者采用温阳通络法辅助治疗,疗效与安全性均良好,可改善患者的临床症状,控制血压水平。Objective:To observe the therapeutic effect of Wenyang Tongluo method in adjuvant treatment of refractory hypertension.Methods:Select 78 patients with intractable hypertension that meet the criteria as the research objects,and randomly divide them into an observation group (n=39) and a control group (n=39).Both groups of patients were given amlodipine besylate + irbesartan hydrochlorothiazide tablets orally,combined with a low-salt and low-fat diet,quit smoking and alcohol,and improve lifestyle.The control group was treated with Tongxinluo capsules orally,and the observation group was treated with Tongxinluo capsules plus traditional Chinese medicine granules with the method of warming Yang and Tongluo.The treatment time of both groups was 12 weeks.The short-term curative effect,TCM syndrome scores (dizziness,headache,palpitations,tongue picture),blood pressure level,blood pressure compliance status,and adverse reactions were compared between the two groups.Results:The total effective rate of TCM syndromes in the observation group was significantly higher than that in the control group (P<0.05).The scores of dizziness,headache,palpitations,and tongue of the two groups after treatment were significantly lower than those before treatment,and the scores of dizziness,headache,palpitations,and tongue of the observation group were significantly lower than those of the control group after treatment (P<0.05).The systolic blood pressure and diastolic blood pressure of the two groups were significantly lower than those before treatment.The systolic blood pressure and diastolic blood pressure of the observation group were significantly lower than those of the control group after treatment (P<0.05).The total effective rate of achieving blood pressure in the observation group was significantly higher than that in the control group (P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion:The adjuvant therapy of warming yang and dredging co

关 键 词：难治性高血压 温阳通络法 通心络胶囊 炮附子 

分 类 号：R255.3[医药卫生—中医内科学]