1-[S-(4-氯苯基)-S-甲基亚砜基]-3-戊基-2-硝基胍的合成  

Synthesis of 1-[(4-Chlorophenyl)(Methyl)(Oxo)-Sulfanylidene]-2-Nitro-3-Pentylguanidine

作　　者：罗梓元 黄诗韵 钟思维 熊茗珺 董宇淏 李洪森[1] LUO Ziyuan;HUANG Shiyun;ZHONG Siwei;XIONG Mingjun;DONG Yuhao;LI Hongsen

机构地区：[1]上海工程技术大学化学化工学院,上海201620

出　　处：《上海化工》2021年第5期19-22,共4页Shanghai Chemical Industry

基　　金：上海工程技术大学大学生创新创业训练计划项目(cx2004001)。

摘　　要：亚砜亚胺衍生物作为农药在农业生产中有广泛的应用。以硝基胍为初始原料,经过取代、氧化偶联等4步反应合成了目标化合物。在氧化偶联反应中,1-戊基硝基胍和苯硫醚的投料比为1∶1.5时,产物收率为72.8%。As pesticide,sulfoximine derivatives have been widely applied in agriculture.In this paper,using nitroguanidine as start material,the target compound was synthesized by substitution and oxidative coupling reaction.In oxadive coupling reaction,when the ratio of 2-nitro-1-pentylguanidine to phenyl sulfide was 1.5︰1.0,the key intermediate was obtained in 72.8%yield.

关 键 词：硝基胍 硫醚 亚砜亚胺 合成 

分 类 号：TQ215[化学工程—有机化工]