Effects of S-adenosylmethionine on production of secondary metabolites in Streptomyces diastatochromogenes 1628  

作　　者：Yefeng HU Juan WANG Jie XU Zheng MA Andreas BECHTHOLD Xiaoping YU 

机构地区：[1]Zhejiang Provincial Key Laboratory of Biometrology and Inspection&Quarantine,College of Life Sciences,China Jiliang University,Hangzhou 310018,China [2]Institute for Pharmaceutical Sciences,Pharmaceutical Biology and Biotechnology,University of Freiburg,79104 Freiburg,Germany

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第9期767-773,共7页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：supported by the Excellent Youth Fund of Zhejiang Province,China(No.LR17C140002)。

摘　　要：Streptomyces are famous for their ability to synthesize a large number of bioactive compounds as secondary metabolites containing antibiotics,enzyme inhibi-tors,and other small molecules with potential physiological activity(Niu et al.,2016;Song et al.,2019;Yin et al.,2019).Secondary metabolites are produced by a multi-step reaction of a primary metabolite as a precursor(Liu et al.,2013;Li et al.,2021).Therefore,it is of great research significance to increase the overall synthesis level of antibiotics by increasing the amount of synthesis of precursors.

关 键 词：SYNTHESIS SYNTHESIZE ochro 

分 类 号：Q936[生物学—微生物学]