多举措干预中药注射剂不合理配伍的效果探讨  

Effects of Multiple Interventions on Irrational Compatibility of Traditional Chinese Medicine Injection

作　　者：高旭 关胜江[1] 马娟娟[1] 董立华[1] 朱梦原 程杰[1] 孙士江[1] GAO Xu;GUAN Shengjiang;MA Juanjuan;DONG Lihua;ZHU Mengyuan;CHENG Jie;SUN Shijiang(Hebei Provincial Hospital of Traditional Chinese Medicine,Hebei Industrial Technology Institute for Traditional Chinese Medicine Preparation,Hebei Shijiazhuang 050000,China)

机构地区：[1]河北省中医院,河北省中药制剂产业技术研究院,河北石家庄050000

出　　处：《中国医院用药评价与分析》2021年第9期1120-1123,共4页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：河北省中医药管理局科研计划项目(No.2020004)。

摘　　要：目的:了解多举措施实施前后国家中医临床研究基地河北省中医院(以下简称"我院")中药注射剂配伍使用情况,提高中药注射剂配伍的安全性和有效性。方法:2020年7月我院开始采用多举措干预中药注射剂不合理医嘱。采用回顾性的方法,调查干预前(2020年1—6月)、干预后(2020年7—12月)的中药注射剂住院医嘱,对不合理配伍医嘱进行统计分析,对比干预前后中药注射剂医嘱配伍不合理率及干预措施的有效性。结果:干预前,18917组中药注射剂医嘱中,不合理配伍医嘱299组,中药注射剂医嘱配伍不合理率为1.58%;干预后,23593组中药注射剂医嘱中,不合理配伍医嘱306组,中药注射剂医嘱配伍不合理率为1.30%(不合理率较干预前降低17.72%)。干预后,中药注射剂不合理配伍医嘱中,医嘱录入错误、中西药混合输注的医嘱数构成比降幅最大,其次为药物剂量选择不当、溶剂剂量选择不当医嘱,表明多举措并用能有效改善中药注射剂医嘱不合理配伍情况。结论:采用信息化手段和行政干预等多种措施PDCA循环管理,对中药注射剂配伍医嘱进行干预,可有效地提高中药注射剂合理配伍水平,为患者用药安全提供保障。OBJECTIVE:To investigate the compatibility of medicines in medical orders from the National Clinical Research Base of Traditional Chinese Medicine Hebei Provincial Hospital of Traditional Chinese Medicine(hereinafter referred to as"our hospital")before and after the implementation of multiple measures,so as to improve the safety and effectiveness of traditional Chinese medicine injection.METHODS:In Jul.2020,our hospital began to implement multiple measures on irrational medical orders of traditional Chinese medicine injection.Retrospective method was adopted to investigate inpatient medical orders of traditional Chinese medicine injection before intervention(from Jan.to Jun.2020)and after intervention(from Jul.to Dec.2020).The irrational compatibility of medical orders was statistically analyzed to compare the irrational compatibility rate of medical orders of traditional Chinese medicine injection and the effectiveness of intervention measures before and after intervention.RESULTS:Before intervention,among 18917 medical orders of traditional Chinese medicine injection,299 were found to have irrational compatibility,and the irrational compatibility rate of traditional Chinese medicine injection was 1.58%.After intervention,among 23593 medical orders of traditional Chinese medicine injection,306 were found to have irrational compatibility,and the irrational compatibility rate of traditional Chinese medicine injection was 1.30%(17.72%lower than before intervention).After intervention,among the irrational compatibility of traditional Chinese medicine injection,the proportion of medical orders decreased the most in the case of incorrect input of medical orders and mixed infusion of Chinese and Western medicines,followed by improper selection of drug dosage and solvent dosage,indicating that multiple measures can effectively improve the irrational compatibility of traditional Chinese medicine injection.CONCLUSIONS:The use of information technology and administrative intervention and other measures of PDCA cycle manage

关 键 词：中药注射剂 配伍 处方审核 合理用药 国家中医临床研究基地 

分 类 号：R932[医药卫生—生药学]