静电纺丝技术对皮肤创面治疗作用的研究进展  

Recent advances in electrospun nanofibers for wound healing

作　　者：陈佳龙 张郭 钟爱梅 赵阳 肖芃 孙家明[1] Chen Jialong;Zhang Guo;Zhong Aimei;Zhao Yang;Xiao Peng;Sun Jiaming(Department of Plastic Surgery,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院整形外科,武汉430022

出　　处：《中华实验外科杂志》2021年第10期2069-2073,共5页Chinese Journal of Experimental Surgery

基　　金：湖北省自然科学基金(2018CFB489)。

摘　　要：纳米纤维静电纺丝支架在再生医学、组织工程、药物递送和创面愈合等生物医学领域中具有广泛的应用潜景。在本文中,我们先对创面进行了简要介绍,然后详述了纳米纤维静电纺丝支架在伤口愈合中的应用,包括缝线、多功能敷料、真皮再生、表皮再生和全层皮肤再生。最后,我们对该领域的研究进行总结和展望。Electrospinning nanofiber scaffolds show great potential in many biomedical applications including regenerative medicine,tissue engineering,drug delivery and wound healing.This article begins with a brief introduction on the wound,and then highlights the application of nanofiber electrospinning scaffolds in wound healing,including sutures,multifunctional dressings,dermal regeneration,epidermalregeneration and full-thickness skin regeneration.Finally,we finish with conclusions and future perspective in this field.

关 键 词：静电纺丝 创面愈合 皮肤组织工程 

分 类 号：R318.08[医药卫生—生物医学工程] R641[医药卫生—基础医学]