Fatigue behavior of cortical bone:a review  

作　　者：Jingwen Li He Gong 

机构地区：[1]Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,Beijing Advanced Innovation Center for Biomedical Engineering,School of Biological Science and Medical Engineering,Beihang University,Beijing 100191,China

出　　处：《Acta Mechanica Sinica》2021年第3期516-526,I0004,共12页力学学报（英文版）

基　　金：This study was supported by the National Natural Science Foundation of China(Grant 11872095);the Natural Science Foundation of Jilin Province(Grant 20200201260JC).

摘　　要：Fatigue is a common cause of bone failure.As the main load-bearing tissue,cortical bone carries a considerable share of load in the whole bone.Under cyclic loading condition,microdamage may generates and accumulates in cortical bone,which further triggers the fracture of bone.It is crucial to explore the fatigue properties of cortical bone and the influential factors for both clinical diagnosis and establishment of models that can predict fatigue failure of human cortical bone.In this review,the fatigue behavior of cortical bone was investigated.Through the complex hierarchical structure and self-repairing process,the risk of catastrophic fracture is reduced.Based on these understandings,the multiple influential factors of cortical bone fatigue properties were analyzed,which were considered to be a combination of internal and external factors.The internal factors include material properties of bone composition(i.e.,mineral,organic material,and water)and bone structure.External factors refer to loading condition such as frequency,amplitude and direction of load.Besides,age,disease,radiation exposure and other factors affect the fatigue behavior of bone by altering one or more factors mentioned above.

关 键 词：Cortical bone FATIGUE MICRODAMAGE Influential factor 

分 类 号：O346.2[理学—固体力学]