三藤四物汤加减联合体外冲击波对骨盆旋移综合征患者影像学指标及血清炎症因子的影响  

Effects of modified Santeng Siwu Decoction combined with extracorporeal shock wave on imaging indexes and serum inflammatory factors in patients with flared pelvis syndrome

作　　者：印杰[1] 曹涤平[1] 李超 顾小华[1] YIN Jie;CAO Diping;LI Chao;GU Xiaohua(The Seventh People’s Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200137, China)

机构地区：[1]上海中医药大学附属第七人民医院,上海200137

出　　处：《现代中西医结合杂志》2021年第28期3126-3130,共5页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的研究三藤四物汤加减联合体外冲击波对骨盆旋移综合征患者影像学指标及血清炎症因子水平的影响。方法选取上海中医药大学附属第七人民医院2015年6月—2019年6月诊治的86例骨盆旋移综合征患者作为研究对象,按随机数字表法分为2组,对照组43例采用抻筋整脊术+体外冲击波治疗,观察组43例在对照组基础上联合三藤四物汤加减治疗。观察比较2组治疗前及治疗3周后影像学指标及血清炎症因子[肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、白细胞介素-18(IL-18)]、视觉模拟疼痛(VAS)评分、Frankel脊髓功能障碍分级,评估2组临床疗效。结果2组治疗后髋骨宽度差、闭孔宽度差、股骨颈长度差、髂嵴高度差及腰骶角均明显缩小,且观察组缩小较对照组更显著,差异均有统计意义(P均<0.05);2组治疗后TNF-α、hs-CRP、IL-6、IL-10和IL-18水平均明显下降,且观察组均明显低于对照组,差异均有统计意义(P均<0.05);观察组治疗后VAS评分低于对照组,Frankel D级占比显著高于对照组,差异均有统计意义(P均<0.05);观察组临床总有效率为100%,对照组为81.40%(35/43),2组比较差异有统计意义(P<0.05)。结论三藤四物汤加减联合体外冲击波疗法能够优化骨盆旋移综合征患者影像学指标,减轻炎症反应和疼痛,改善脊髓功能障碍,提升临床疗效。Objective It is to study the effect of modified Santeng Siwu Decoction combined with extracorporeal shock wave on imaging indexes and serum inflammatory factors in patients with flared pelvis syndrome.Methods Eighty-six patients with flared pelvis syndrome treated in the Seventh People’s Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from June 2015 to June 2019 were selected as the research objects,and they were divided into two groups according to the random number table method.43 cases in the control group were treated with stretched chiropractic+extracorporeal shock wave,43 cases in the observation group were combined with Santeng Siwu Decoction on the basis of the control group.The imaging indicators and serum inflammatory factors including tumor necrosis factor-α(TNF-α),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),white blood cell interleukin-10(IL-10)and interleukin-18(IL-18),visual analog pain(VAS)score,Frankel spinal cord dysfunction classification before treatment and after treatment for 3 weeks were observed and compared in the two groups,and the clinical efficacy was assessed.Results The hip bone width difference,obturator width difference,femoral neck length difference,iliac crest height difference,and lumbosacral angle were significantly reduced after treatment in the two groups,and the reduction in the observation group was more significant compared with the control group,the differences were statistically significant(all P<0.05);the levels of TNF-α,hs-CRP,IL-6,IL-10 and IL-18 were decreased significantly after treatment in the two groups,and the levels in the observation group was lower than those in the control group,the differences were statistically significant(all P<0.05);after treatment,the VAS score of the observation group was lower and the proportion of Frankel D grade was significantly higher than that of the control group,the differences were statistically significant(all P<0.05);the total clinical effective rate of the observation group

关 键 词：骨盆旋移综合征 三藤四物汤 体外冲击波 影像学指标 炎症因子 

分 类 号：R681.6[医药卫生—骨科学]