获得性中耳胆脂瘤基础研究进展  

Advances in Basic Research on Acquired Middle Ear Cholesteatoma

作　　者：吴华东[1] 熊园平[1] 江红群[1] WU Huadong;XIONG Yuanping;JIANG Hongqun(Department of Otolaryngology Head and Neck Surgery,First Affiliated Hospital of Nanchang University,Nanchang,330006,China)

机构地区：[1]南昌大学第一附属医院耳鼻咽喉头颈外科,南昌330006

出　　处：《中华耳科学杂志》2021年第5期833-836,共4页Chinese Journal of Otology

基　　金：Experimental research of bone marrow mesenchymal stem cells(No.811208677017)

摘　　要：获得性中耳胆脂瘤是一种良性的、具有局部侵袭性的颞骨内囊性病变。其常见的临床表现有耳流脓、耳臭、听力下降等,当侵袭周围组织结构则可产生眩晕、周围性面瘫、颅内感染等一系列并发症甚至危及生命的可能。手术仍然是目前唯一有效的治疗方法,但寻求手术以外的新的治疗方法是未来临床和实验研究的重点,本文就获得性中耳胆脂瘤相关基础研究进展进行综述。Acquired middle ear cholesteatoma is a benign and locally invasive cystic lesion of the temporal bone.Common clinical manifestations include ear discharge,odor,hearing loss and more.When it invades surrounding struc-tures,complications,such as vertigo,peripheral facial paralysis,intracranial infections and even death can happen.Sur-gery remains the only available treatment now,although new non-surgical therapeutic choices for cholesteatoma may be-come the focus of clinical and experimental research in the future.This article reviews advances in basic research on ac-quired middle ear cholesteatoma.

关 键 词：胆脂瘤 获得性 细胞因子 干细胞 

分 类 号：R764[医药卫生—耳鼻咽喉科]