乙肝疫苗免疫应答效果的研究进展  

Research Progress on Immune Response Effect of Hepatitis B Vaccine

作　　者：陆玉英 梁才峰 林建培 陆慧 王慧娜 李海 

机构地区：[1]广西中医药大学公共卫生与管理学院,广西南宁530001

出　　处：《大众科技》2021年第8期47-51,7,共6页Popular Science & Technology

基　　金：国家自然科学基金项目(81760604);广西中医药大学大学生校级课题(2019DXS18);广西中医药大学研究生教育创新计划资助项目(YCSZ2020020)。

摘　　要：乙肝疫苗于2002年纳入儿童计划免疫,是目前预防乙肝最安全、经济有效的方法。但在人群中仍会出现无(弱)应答现象,并且乙肝疫苗的效用时期并非永久。近年来,国内外研究者对乙肝疫苗无(弱)应答的影响因素已有较为丰富的研究,文章就目前关于乙肝疫苗免疫应答效果的研究成果进行综述,总结其目前的研究进展,探讨提高乙肝疫苗免疫应答的策略和措施,进而发掘新的研究方向,为科学研究提供新的线索,以期为免疫规划工作提供科学性的理论依据。Hepatitis B vaccine was introduced into children’s planned immunization in 2002.It is the most safe,economical and effective way to prevent hepatitis B.However,there will be no(weak)response in the crowd,and the duration of the hepatitis B vaccine is not permanent.In recent years,researchers at home and abroad have made extensive researches on the factors influencing the no(weak)response of hepatitis B vaccine.The article summarizes the current research progress on the effect of hepatitis B vaccine immune response,summarizes the current research progress,explores strategies and measures to improve the immunization of hepatitis B vaccine,and further explores new research directions,so as to provide new clues for scientific research,in order to provide scientific theoretical basis for immunization program.

关 键 词：乙肝疫苗 免疫应答效果 再免疫作用 

分 类 号：R512.6[医药卫生—内科学]