胰岛素泵在妇科2型糖尿病患者围手术期的应用效果分析  

Analysis of the effect of continuous subcutaneous insulin infusion on gynecological patients with type 2 diabetes mellitus during perioperative period

作　　者：肖莹 白枫[1] 李辉[1] XIAO Ying;BAI Feng;LI Hui(Department of Gynecology,Liaoning People’s Hospital,Shenyang 110000,China)

机构地区：[1]辽宁省人民医院妇科,110000

出　　处：《中国实用医药》2021年第28期115-118,共4页China Practical Medicine

摘　　要：目的 比较胰岛素泵(CSII)与多次皮下注射胰岛素(MSII)在妇科2型糖尿病患者围手术期的临床疗效。方法 80例妇科择期手术合并2型糖尿病患者,根据围手术期治疗方式不同分为试验组(25例)和对照组(55例)。试验组采用胰岛素泵皮下注射治疗,对照组采用多次皮下注射胰岛素治疗。对比两组治疗前、术前1 d的血糖指标,不同时间段空腹血糖(FBG),术前控制血糖时间、低血糖发生率、胰岛素用量、住院时间、术后感染发生率及切口愈合时间。结果 术前1 d,两组FBG及餐后2 h血糖(2 h PG)均较治疗前下降,差异有统计学意义(P<0.05);术后第1、2天,试验组FBG分别为(8.63±0.72)、(8.97±1.42)mmol/L,均低于对照组的(9.81±2.44)、(10.82±2.76)mmol/L,差异有统计学意义(P<0.05)。试验组术前控制血糖时间、切口愈合时间、住院时间均短于对照组,低血糖发生率、术后感染发生率均低于对照组,差异有统计学意义(P<0.05);试验组胰岛素用量少于对照组,但差异无统计学意义(P>0.05)。结论 胰岛素泵更能平稳有效地控制妇科糖尿病患者围手术期的血糖,减少低血糖及术后感染的发生。Objective To compare the clinical efficacy between continuous subcutaneous insulin infusion(CSII)and multiple subcutaneous insulin injection(MSII)on gynecological patients with type 2 diabetes mellitus(T2DM)during perioperative period.Methods A total of 80 patients with elective gynecological surgery combined with type 2 diabetes mellitus were divided into experimental group(25 cases)and control group(55 cases)according to the different perioperative treatment methods.The experimental group was treated by continuous subcutaneous insulin infusion,and the control group was treated by multiple subcutaneous insulin injection.Both groups were compared in terms of blood glucose indicators before treatment and 1 d before surgery,fasting blood glucose(FBG)at different time periods,time to control blood glucose before surgery,incidence of hypoglycemia,insulin dosage,hospitalization time,incidence of postoperative infection and incision healing time.Results 1 d before surgery,FBG and 2 h postprandial glucose(2 h PG)in the two groups were lower than those before treatment,and the difference was statistically significant(P<0.05).On the 1st and 2nd day after surgery,FBG of the experimental group were(8.63±0.72)and(8.97±1.42)mmol/L,respectively,which were lower than(9.81±2.44)and(10.82±2.76)mmol/L of the control group,and the difference was statistically significant(P<0.05).The time to control blood glucose before surgery,incision healing time and hospitalization time of the experimental group were shorter than those of the control group,and the incidence of hypoglycemia and postoperative infection were lower than those of the control group.All the differences were statistically significant(P<0.05).The insulin dosage in the experimental group was less than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion Continuous subcutaneous insulin infusion can more steadily and effectively control the perioperative blood glucose of gynecological patients with type 2 diabetes mellitus du

关 键 词：胰岛素泵 2型糖尿病 妇科 围手术期 

分 类 号：R587.1[医药卫生—内分泌] R619[医药卫生—内科学]