一种高重复频率激发电路下的高速超声内窥成像系统  

High-Speed Ultrasound Endoscopic Imaging System Based on High Repetition Frequency Transmit Circuit

作　　者：张建辉[1] 杨冠宇 牛超君 龚小竞[2] 舒承有 张帆 桂珍珍 ZHANG Jianhui;YANG Guanyu;NIU Chaojun;GONG Xiaojing;SHU Chengyou;ZHANG Fan;GUI Zhenzhen(School of Mechanical and Electrical Engineering,Guangzhou University,Guangzhou 510006,China;Research Lab for Biomedical Optics and Molecular Imaging,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China)

机构地区：[1]广州大学机械与电气工程学院,广州510006 [2]中国科学院深圳先进技术研究院生物医学光学与分子影像研究室,深圳518055

出　　处：《数据采集与处理》2021年第5期891-897,共7页Journal of Data Acquisition and Processing

基　　金：国家自然科学基金(51705593)资助项目。

摘　　要：光学相干层析?血管内超声联合(Optical coherence tomography intravascular ultrasound,OCT?IVUS)成像技术能同时弥补光学相干涉成像的低成像深度与超声成像的低分辨率,能够较为全面地进行血管内的易损斑块识别,但受血管内超声(Intravascular ultrasound,IVUS)技术超声激发重复频率限制,OCT?IVUS成像难以在高帧率成像的同时获得高成像线数,从而影响显示分辨率。为提升IVUS成像速度,同时不降低图像显示的分辨率,尝试应用高重频超声激发技术的方法解决这一难题。本文设计了一种50 kHz的高重频超声激发电路,并在此设计基础上研制了一种50 f/s的高速超声内窥成像系统;进而对系统性能进行测试。激发电路高压脉冲测试以及信噪比(Signal noise ratio,SNR)测试结果表明:激发电路可用于25 MHz超声换能器的激发,具有较高的SNR;应用此激发电路所研制的超声内窥成像系统能够在不降低显示分辨率的前提下提高成像速度,该系统技术能有效检出易损斑块,促进OCT?IVUS的临床应用,对心血管疾病的早期发现、诊断和预防具有一定价值。Optical coherence tomography intravascular ultrasound(OCT-IVUS)imaging can compensate for the low imaging depth of optical phase interference imaging and the low resolution of ultrasound imaging,and can comprehensively identify vulnerable plaques in blood vessels.However,due to the limitation of the IVUS ultrasound transmitting repetition frequency,it is difficult for OCT-IVUS imaging to ensure a large number of A-line acquisitions while performing high-frame-rate imaging,thereby limiting the display resolution.To improve the imaging speed of IVUS without reducing the resolution of image display,a high-repetition ultrasound excitation method is applied to solve this problem.Here,an ultrasound transmit circuit with a 50 kHz repetition frequency is designed to improve the imaging speed of IVUS,and a high-speed ultrasonic endoscopic imaging system with 50 f/s is developed based on this circuit.The high-voltage pulse test and the signal noise ratio(SNR)test proved that the transmit circuit is able to excite a 25 MHz transducer while obtaining a signal with high SNR.The transmit circuit can be used for the excitation of 25 MHz ultrasound transducers and has a high SNR;the ultrasound endoscopic imaging system developed by the application of this excitation circuit can increase the imaging speed without reducing the display resolution.The system has clinical application value for improving the effective use of OCT-IVUS,early detection,diagnosis,and prevention of cardiovascular diseases,and has a promoting effect on the detection of vulnerable plaques.

关 键 词：超声成像 超声激发 高速成像 血管内超声成像 光学相干层析?血管内超声联合成像 

分 类 号：O433[机械工程—光学工程] TB57[理学—光学]