脂肪干细胞在皮肤损伤再生及组织工程中的应用及进展  

Application and progress of adipose stem cells in skin injury and regeneration and tissue engineering

作　　者：朱亮 林享玉 何晶[1] Zhu Liang;Lin Xiangyu;He Jing(Department of Pathology and Pathophysiology,School of Medicine,Tongji University,Shanghai 200092,China)

机构地区：[1]同济大学医学院病理和病理生理学系,上海200092

出　　处：《解剖学杂志》2021年第5期433-437,共5页Chinese Journal of Anatomy

基　　金：上海市卫生健康委员会卫生行业临床研究专项面上项目(202040027);上海市大学生创新活动计划项目(S202014009,S202110247140);国家级大学生创新活动计划项目(202110247136)。

摘　　要：皮肤损伤尤其是大面积皮肤缺损,是临床难以解决的问题。组织工程化皮肤构建则是有效途径之一。而脂肪干细胞(ASCs)作为成体间充质干细胞之一,因获得量大、供区损伤小及免疫原性低等独特优势,被认为在皮肤再生及组织工程中具有重要的应用潜力。现主要从ASCs在皮肤损伤再生及组织工程中的应用及其相关进展等方面进行论述。Skin injury,especially large area skin defect,is a difficult problem to be solved in clinic.Tissue engineering skin construction is one of the effective ways to solve this problem.Adipose tissue-derived stem cells(ASCs)have been considered to have important application potential in skin regeneration and tissue engineering because of their unique advantages such as large quantity,small donor site injury,and low immunogenicity.This paper mainly discusses the application and related progress of ASCs in skin injury and regeneration and tissue engineering.

关 键 词：脂肪干细胞 皮肤再生 组织工程 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]