心肌细胞株的特性及其在心血管疾病研究中的应用  

Characteristics of myocardial cell lines and their application in cardiovascular disease research

作　　者：田香勤[1] 郭志坤[1] Tian Xiangqin;Guo Zhikun(Henan Key Laboratory of Medical Tissue Regeneration,Xinxiang Medical University,Xinxiang 453003,China)

机构地区：[1]新乡医学院河南省医用组织再生重点实验室,新乡453003

出　　处：《解剖学杂志》2021年第5期437-441,共5页Chinese Journal of Anatomy

基　　金：国家自然科学基金(81570268);新乡医学院博士启动基金。

摘　　要：心肌细胞株是研究心血管疾病发病机制和药物筛选的重要材料,不同的心肌细胞株其生物学特性存在较大差异。在心血管疾病研究中,心肌细胞株的选择与研究结果密切相关。现围绕当前心肌细胞株的生物学特性及其在研究中的应用展开综述,并提出了研究展望,以进一步拓展对于心肌细胞株的认识,为心血管疾病研究提供参考。Myocardial cell lines are essential materials for studying the pathogenesis of cardiovascular diseases and drug screening.These cell lines function are different due to their individual biological characteristics.In the study of cardiovascular diseases,the selection of myocardial cell lines af fects the research results.In this article,the biological characteristics and application of several myocardial cell lines were reviewed,and the research prospects were put forward to further expand the understanding of myocardial cell lines,which provides references for further study of cardiovascular diseases.

关 键 词：心肌细胞株 H9C2细胞 HL-1细胞 AC16细胞 心血管疾病 

分 类 号：R54[医药卫生—心血管疾病]