Highly antifouling double network hydrogel based on poly(sulfobetaine methacrylate)and sodium alginate with great toughness  

作　　者：Jing Zhang Sunxiang Qian Lingdong Chen Liqun Chen Liping Zhao Jie Feng 

机构地区：[1]College of Materials Science&Engineering,Zhejiang University of Technology,Hangzhou,310014,China [2]The Second Affiliated Hospital of Jiaxing University,Jiaxing,314000,China

出　　处：《Journal of Materials Science & Technology》2021年第26期235-244,共10页材料科学技术（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(Nos.52073256,21404091 and 21404089);the Zhejiang Provincial Natural Science Foundation of China(No.LBY21E030001)。

摘　　要：Hydrogels with good antifouling and mechanical properties as well as biocompatibility have great application potential in the field of biomedicine.In this paper,a newly double network(DN)hydrogel was prepared based on zwitterionic material sulfobetaine methacrylate(SBMA)and natural polysaccharide,sodium alginate(SA).The PSBMA network is covalently crosslinked while the SA network is ionically crosslinked by Ca^(2+).The hybrid crosslinked double network structure endows the DN hydrogel with excellent mechanical properties(E=0.19±0.01 MPa,σ=0.73±0.03 MPa),fast self-recovery ability as well as excellent fatigue resistance.Moreover,the results show that the PSBMA/SA-Ca^(2+)DN hydrogel is biocompatible and resists the absorption of non-specific proteins and adhesion of microorganisms,such as cells and algae,exhibiting outstanding antifouling properties.These unique characteristics of PSBMA/SA-Ca^(2+)DN hydrogel make it a promising candidate for biomedical application,such as artificial connective tissues,implantable devices,and underwater equipment.

关 键 词：Double network hydrogel ANTIFOULING Mechanical properties ZWITTERIONIC 

分 类 号：TQ427.26[化学工程]