滑膜炎颗粒联合注射玻璃酸钠治疗膝骨关节炎合并滑膜炎的临床效果  

Clinical effect of Synovitis Granules combined with Sodium Hyaluronate Injection in the treatment of knee osteoarthritis complicated with synovitis

作　　者：吴天林 王玮佳 张銮弟 陈秀娟 李昌宁 WU Tian-lin;WANG Wei-Jia;ZHANG Luan-di;CHEN Xiu-juan;LI Chang-Ning(Department of Orthopedics and Traumatology,the Third People′s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fujian Province,Fuzhou350108,China)

机构地区：[1]福建中医药大学附属第三人民医院骨伤科,福建福州350108

出　　处：《中国当代医药》2021年第29期85-87,共3页China Modern Medicine

基　　金：福建中医药大学校管科研课题(XB2019052)。

摘　　要：目的探讨滑膜炎颗粒联合注射玻璃酸钠治疗膝骨关节炎(KOA)合并滑膜炎的临床效果。方法选取2019年7月至2020年7月福建中医药大学附属第三人民医院收治的KOA合并滑膜炎患者60例作为研究对象,按照随机数字表法分为对照组和治疗组,每组各30例。对照组予以注射玻璃酸钠,治疗组予以注射玻璃酸钠注射+口服滑膜炎颗粒。比较两组的治疗效果,治疗前后的视觉模拟评分法(VAS)评分及关节肿胀度。结果治疗组的总有效率为83.3%,高于对照组的76.7%,差异有统计学意义(P<0.05)。治疗前两组患者的VAS评分及膝关节肿胀度评分比较,差异无统计学意义(P>0.05)。治疗后两组的VAS评分及膝关节肿胀度评分均低于治疗前,且试验组的VAS评分及膝关节肿胀度评分均低于对照组,差异有统计学意义(P<0.05)。结论滑膜炎颗粒联合注射玻璃酸钠治疗KOA合并滑膜炎疗效显著,具有临床推广价值。Objective To investigate the clinical effect of Synovitis Granules combined with Sodium Hyaluronate Injection in the treatment of knee osteoarthritis(KOA)combined with synovitis.Methods A total of 60 patients with KOA complicated with synovitis admitted to the Third People′s Hospital Affiliated to Fujian University of Chinese Medicine from July 2019 to July 2020 were selected as the research subjects,and they were divided into control group and treatment group according to random number table method,with 30 cases in each group.The control group was injected with Sodium Hyaluronate,and the treatment group was injected with Sodium Hyaluronate+Synovitis Granules orally.The treatment effect,visual analogue scale(VAS)score and joint swelling degree before and after treatment were compared between the two groups.Results The total effective rate of the treatment group was 83.3%,higher than that of the control group(76.7%),and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in VAS score and knee swelling score between two groups(P>0.05).After treatment,VAS score and knee swelling score in the two groups were lower than before,and VAS score and knee swelling score in the experimental group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion The combination of Synovitis Granules and Sodium Hyaluronate has a significant effect on the treatment of KOA combined with synovitis,which has clinical promotion value.

关 键 词：滑膜炎颗粒 玻璃酸钠 膝骨关节炎 滑膜炎 

分 类 号：R684.3[医药卫生—骨科学]