针刺联合化瘀通脉消痹汤对脑梗死患者病情转归及血清生化指标的影响  

Effect of Acupuncture and Moxibustion Combined with Huayu Tongmai Xiaobi Decoction on Prognosis and Serum Biochemical Indicators of Cerebral Infarction Patients

作　　者：杨秀娟[1] 解衍龙 侯春光[1] YANG Xiujuan;XIE Yanlong;HOU Chunguang(Department of Acupuncture and Moxibustion,Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine,Tianjin 300120,China)

机构地区：[1]天津市中医药研究院附属医院针灸一科,天津300120

出　　处：《光明中医》2021年第17期2947-2950,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的研究针刺联合化瘀通脉消痹汤对脑梗死患者病情转归及血清生化指标的影响。方法选择2019年1月—2020年6月收治的脑梗死患者150例作为研究对象,随机分为A、B、C组,在常规西医治疗的基础上A组接受针刺治疗、B组接受化瘀通脉消痹汤治疗、C组接受针刺联合化瘀通脉消痹汤治疗。比较3组美国国立卫生研究院卒中量表(NIHSS)评分、中医证候积分及血清生化指标的差异。结果3组患者治疗后的NIHSS评分、中医证候积分及血清总胆固醇(TC)、低密度脂蛋白胆固醇(LCL-C)含量均低于治疗前,血清脑源性神经营养因子(BDNF)、胰岛素样生长因子-1(IGF-1)、血管内皮生长因子(VEGF)均高于治疗前且C组患者治疗后的NIHSS评分、中医证候积分及血清TC、LDL-C含量均低于A组、B组,血清BDNF、IGF-1、VEGF均高于A组、B组。结论针刺联合化瘀通脉消痹汤能够改善脑梗死患者的神经功能并调节血脂代谢、增加生长因子分泌。Objective To study the effect of acupuncture combined with Huayu Tongmai Xiaobi decoction on the prognosis and serum biochemical indexes of cerebral infarction patients.Methods 150 patients with cerebral infarction admitted to our hospital from September 2017 to January 2019 were randomly divided into group A,group B and group C.On the basis of conventional Western medicine,group A received acupuncture,group B received Huayu Tongmai Xiaobi Decoction,and group C received acupuncture combined with Huayu Tongmai Xiaobi decoction.The differences of NIHSS score,TCM syndrome score and serum biochemical indexes were compared among the 3 groups.Results After treatment,the NIHSS score,TCM syndrome score,serum total cholesterol(TC)and low density lipoprotein cholesterol(LCL-C)levels in the three groups were lower than those before treatment,the serum brain-derived neurotrophic factor(BDNF),insulinlike growth factor-1(IGF-1),vascular endothelial growth factor(VEGF)levels were higher than those before treatment,and the NIHSS score,TCM syndrome score,serum TC and LDL-C levels of group C were significantly lower than those of group A and group B,and serum BDNF,IGF-1 and VEGF levels were higher than those of group A and group B.Conclusion Acupuncture combined with Huayu Tongmai Xiaobi decoction can improve neurological function,regulate blood lipid metabolism and increase growth factor secretion in patients with cerebral infarction.

关 键 词：脑梗死 针刺疗法 化瘀通脉消痹汤 中医综合疗法 

分 类 号：R277.7[医药卫生—中医学]