HIV感染与牙周疾病相关性的研究进展  

Research progress of the correlation between human immunodeficiency virus infection and chronic periodontitis

作　　者：李娜[1] 池明翰 李祥伟[1] LI Na;CHI Minghan;LI Xiangwei(Department of Endodontics,Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院牙体牙髓病科,吉林长春130021 [2]吉林大学口腔医院种植科,吉林长春130021

出　　处：《口腔医学》2021年第9期861-864,共4页Stomatology

基　　金：吉林省卫健委科研项目(2017J065,2018J112);吉林省教育厅研究项目(JJKH20180229KJ)。

摘　　要：艾滋病(AIDS)是由感染人类免疫缺陷病毒(HIV)引起的人体免疫功能缺陷疾病,近年来,与艾滋病相关的慢性疾病的研究引发了学者的广泛关注。人们对与HIV相关的慢性病及其相互关系的研究日益增多。HIV感染后很长一段时间没有明显的临床症状,但多数患者在早期就可能出现各种口腔病损,如白色念珠菌病、口腔毛状白斑、HIV相关性牙周病变、卡波西肉瘤以及非霍奇金淋巴瘤等,其中HIV相关性牙周病变较常见。因此,通过牙周组织检查对艾滋病的早期发现具有重要意义。本文将从HIV感染患者的牙周病变表现以及艾滋病与牙周病变发展的关系予以综述。Acquired immunodeficiency syndrome(AIDS)is a human immunodeficiency disease caused by human immunodeficiency virus(HIV)infection,which has aroused much attention since its first onset.A growing interest in the study of chronic manifestations associated with HIV-1 infection has emerged and much attention from scholars has been paid to it during the last few years.There are no obvious clinical symptoms after HIV infection for a long time,but most patients may develop various oral lesions at early stages,such as oral candidiasis,oral hairy leukoplakia,periodontal diseases,Kaposi’s sarcoma and non-Hodgkinlymphoma.HIV-type periodontal disease is the most common among them.Therefore,accurate diagnosis of periodontal diseases is of great significance for the early detection of AIDS.This article intends to review the periodontal disease manifestations of HIV infected patients and the relationship between AIDS and periodontal disease development.

关 键 词：人类免疫缺陷病毒 艾滋病 牙周病 免疫反应 细胞因子 

分 类 号：K781.4[历史地理—历史学]