老年肺炎合并静脉血栓栓塞症的临床特征及其危险因素分析  

Clinical characteristics and risk factors of senile pneumonia complicated with venous thromboembolism

作　　者：张玉娇 刘争 王娜娜[1] 高璠[1] 谭效锋[1] ZHANG Yu-jiao;LIU Zheng;WANG Na-na(Department of General Medicine,Tianjin Hospital,Tianjin 300211,China.;不详)

机构地区：[1]天津医院普内科,天津300211 [2]中国人民解放军93534部队,天津301799

出　　处：《中国处方药》2021年第10期154-156,共3页Journal of China Prescription Drug

摘　　要：目的观察老年肺炎合并静脉血栓栓塞症(VTE)患者的临床特征,并分析其危险因素,为其预防和治疗提供理论依据。方法选取肺炎合并VTE的老年患者纳入VTE组,选取同期未合并VTE的老年肺炎患者纳入非VTE组,比较两组患者的临床特征和实验室检查结果,并进行危险因素分析。结果VTE组吸烟、卧床>5 d、发热>3 d、合并冠心病、心衰、脑卒中、COPD、呼衰、应用利尿剂的患者人数比例明显高于非VTE组(P<0.05),VTE组化验指标CRP、N%、M、RBC、Hb、MPV、D-Dimer较非VTE组明显升高,ALB、CHE降低(P<0.05)。多变量Logistic回归分析结果显示,吸烟、卧床>5 d、发热>3 d、合并COPD、高D-Dimer水平是老年肺炎合并VTE的独立危险因素。结论吸烟、卧床>5 d、发热>3 d、合并COPD、高D-Dimer水平是老年肺炎患者发生VTE的危险因素。因此,对于这类患者,应尽早行静脉血管超声检查,帮助确诊。Objective To observe the clinical characteristics of elderly patients with pneumonia complicated with venous thromboembolism(VTE),and analyze its risk factors,so as to provide theoretical basis for its prevention and treatment.Methods Elderly patients with pneumonia complicated with VTE were included in the VTE group,and elderly patients with pneumonia without VTE were included in the non-VTE group.The clinical characteristics and laboratory examination results of the two groups were compared,and risk factors were analyzed.Results The proportion of smoking,bedridden>5 d,fever>3 d,coronary heart disease,heart failure,stroke,COPD,respiratory failure and diuretic application in VTE group was significantly higher than that in the non-VTE group(P<0.05),CRP,N%,M,RBC,Hb,MPV,D-Dimer in VTE group were significantly higher than those in non-VTE group,while ALB,CHE were significantly lower(P<0.05).Multivariate Logistic regression analysis showed that smoking,bed ridden>5 d,fever>3 d,COPD and high D-Dimer level were independent risk factors for senile pneumonia complicated with VTE.Conclusion Smoking,bedridden>5 d,fever>3 d,COPD and high D-Dimer level are risk factors for VTE in elderly patients with pneumonia.Therefore,for these patients,venous ultrasound should be performed as soon as possible to help diagnose the disease.

关 键 词：老年肺炎 静脉血栓栓塞症 临床特征 危险因素 

分 类 号：R563.1[医药卫生—呼吸系统] R543.6[医药卫生—内科学]