急性加重期慢性阻塞性肺疾病合并肺性脑病的急救措施评估与临床研究  

Evaluation and Clinical Study on First-aid Measures for Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Pulmonary Encephalopathy

作　　者：张妍 荣阳 ZHANG Yan;RONG Yang(Department of ICU Ward,Liaoyang Central Hospital,Liaoyang 111000,China;Department of Medical,Liaoyang Central Hospital,Liaoyang 111000,China)

机构地区：[1]辽宁省辽阳市中心医院ICU病房,辽宁辽阳111000 [2]辽宁省辽阳市中心医院医务处,辽宁辽阳111000

出　　处：《中国医药指南》2021年第28期70-71,74,共3页Guide of China Medicine

摘　　要：目的分析对急性加重期慢性阻塞性肺疾病(AECOPD)合并肺性脑病患者给予临床急救的方法及效果。方法选择136例慢性阻塞性肺疾病且为急性加重期的患者作为研究对象,所有患者均伴有肺性脑病,根据治疗方法的不同将患者分为两组,对照组66例给予常规临床治疗和BiPAP通气,治疗组70例在对照组的基础上给予纳洛酮治疗,比较两组患者的治疗效果。结果经过治疗后,治疗组患者的意识障碍改善率明显高于对照组(χ^(2)=6.000,P=0.014),气管插管率较对照组低(χ^(2)=4.088,P=0.043);治疗48 h后,治疗组患者的PaO_(2)、PaCO_(2)较对照组改善效果更好,差异有统计学意义(P<0.05)。结论利用BiPAP联合呼吸兴奋剂治疗AECOPD合并肺性脑病患者相比于单独使用BiPAP的效果好。Objective To analyze the methods and effects of clinical first aid for patients with acute exacerbation of chronic obstructive pulmonary disease complicated with pulmonary encephalopathy.Methods A total of 136 patients with acute exacerbation of chronic obstructive pulmonary disease were selected as the research object.All patients were accompanied with pulmonary encephalopathy.According to different treatment methods,the patients were divided into two groups.66 cases in the control group were given routine clinical treatment and BiPAP ventilation,and 70 cases in the treatment group were given naloxone on the basis of the control group.The treatment effects of the two groups were compared.Results After treatment,the improvement rate of consciousness disorder in the treatment group was significantly higher than that in the control group(χ^(2)=6.000,P=0.014),and the rate of endotracheal intubation was lower than that of the control group(χ^(2)=4.088,P=0.043);after 48 hours of treatment,the improvement effect of PaO_(2) and PaCO_(2) in the treatment group is better than that in the control group,the difference was statistically significant(P<0.05).Conclusion BiPAP combined with respiratory stimulant in the treatment of acute exacerbation of chronic obstructive pulmonary disease with pulmonary encephalopathy is more effective than BiPAP alone.

关 键 词：慢性阻塞性肺疾病 急性加重期 肺性脑病 急救措施 疗效评估 

分 类 号：R563.8[医药卫生—呼吸系统]