低分子肝素治疗妊娠中晚期羊水过少的临床疗效观察  

Clinical Observation of Low Molecular Weight Heparin in the Treatment of Oligohydramnios in the Second and Third Trimester of Pregnancy

作　　者：王海霞 WANG Haixia(Shenyang School of Traditional Chinese Medicine,Shenyang 110300,China)

机构地区：[1]沈阳市中医药学校,辽宁沈阳110300

出　　处：《中国医药指南》2021年第28期101-102,共2页Guide of China Medicine

摘　　要：目的探讨低分子肝素治疗妊娠中晚期羊水过少的临床疗效。方法选择我院于2018年1月至2019年1月收治的90例妊娠中晚期羊水过少产妇作为研究的对象,随机数字表法分为对照组和观察组,每组45例,对照组产妇采取静脉补液方法治疗,观察组产妇采取低分子肝素治疗,记录两组患者临床疗效,比较两组患者自然分娩率及剖宫产率,比较两组患者羊水指数(Amniotic Fluid Index,AFI)、脐动脉血流阻力(S/D)、新生儿阿氏评分(Apgar评分)。结果观察组自然分娩率、剖宫产率分别为71.11%、28.89%,对照组则分别为44.44%、55.56%,观察组自然分娩率明显高于对照组,剖宫产率则明显低于对照组,差异具备统计学意义(P<0.05)。治疗前两组AFI、S/D两项指标水平比较无明显差异(P>0.05),治疗后观察组AFI明显高于对照组,S/D则明显低于对照组,差异具备统计学意义(P<0.05)。观察组总有效率95.56%高于对照组的84.44%,差异具备统计学意义(P<0.05)。结论妊娠中晚期羊水过少产妇采取低分子肝素治疗疗效显著,可提高自然分娩率,降低剖宫产率,改善AFI及S/D指标水平,提高新生儿Apgar评分,确保母婴安全及健康,值得采纳及应用。Objective To investigate the clinical efficacy of low molecular heparin on excessive amniotic fluid in the middle and late pregnancy.Methods We selected 90 late amniotic fluid admitted in January 2018 to January 2019 as the study,randomized digital table was divided into control and observation groups,45 women treated by intravenous fluid,low molecular heparin,recorded the clinical efficacy,natural delivery rate and cesarean section rate,compared the amniotic fluid index(AFI),umbilical artery blood flow resistance(S/D),and neonatal steni score(Apgar Evaluation Points).Results The natural delivery rate and cesarean section rate in the observation group were 71.11% and 28.89%,respectively,and the control group were 44.44% and 55.56%,respectively.The natural delivery rate was significantly higher than that of the control group,and the cesarean section rate was significantly lower than the control group,which was statistically significant(P<0.05).There was no significant difference between the two AFI,S/D levels before treatment(P>0.05),AFI was observed significantly higher after treatment,and S/D significantly lower than control,which was statistically significant(P<0.05).The total effective rate in the observation group was 95.56%,which was higher than 84.44% in the control group(P<0.05).Conclusion Excessive amniotic fluid intake in the middle and late pregnancy Taking low molecular heparin treatment has significant efficacy,which can improve the natural delivery rate,reduce the cesarean section rate,improve the level of AFI and S/D indicators,improve the neonatal Apgar score,and ensure the safety and health of mother and baby,which is worthy of adoption and application.

关 键 词：妊娠中晚期 低分子肝素 羊水过少 临床治疗效果 

分 类 号：R714.25[医药卫生—妇产科学]