血清心肌酶水平在新生儿高胆红素血症诊断中的临床意义  

The clinical significance of the serum myocardial enzyme level in the diagnosis of neonatal hyperbilirubinemia

作　　者：张茜[1] 齐秀花 王明园 ZHANG Qian;QI Xiuhua;WANG Mingyuan(Department of Disease Control,the Seventh People’s Hospital of Zhengzhou,Zhengzhou 450000,China)

机构地区：[1]郑州市第七人民医院疾控科,郑州450000

出　　处：《上海医药》2021年第19期35-38,共4页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:探讨血清心肌酶水平在新生儿高胆红素血症诊断中的临床意义。方法:选取新生儿高胆红素血症患儿92例作为研究组,依据总胆红素(TBil)水平分为轻度组、中度组、重度组;选取同期健康新生儿30例为对照组。检测血清心肌酶水平,比较不同病情程度患儿各项指标的差异。结果:血清心肌酶水平比较,研究组高于对照组,重度组高于轻度组、中度组,且中度组各项指标高于轻度组(P<0.05)。血清心肌酶水平与TBil水平呈正相关。结论:血清心肌酶在新生儿高胆红素血症中呈高表达,心肌酶谱指标可诊断病情程度还能够对治疗效果进行评价。Objective:To explore the clinical significance of serum myocardial enzyme levels in the diagnosis of neonatal hyperbilirubinemia.Methods:Ninety-two neonates with hyperbilirubinemia were selected as a study group,which were divided into a mild subgroup,a moderate subgroup and a severe subgroup based on their total bilirubin(TBil)levels,and the other 30 healthy newborns were selected as a control group.Serum myocardial enzyme levels were determined and the differences in the indicators of children with different disease conditions were compared.Results:Serum myocardial enzyme levels were higher in the study group than the control group and in the severe subgroup than the mild group and the moderate group,and the indicators were higher in the moderate group than the mild group(P<0.05).Serum myocardial enzyme levels were positively correlated with TBil levels.Conclusion:Serum myocardial enzyme is high-expressed in the children with neonatal hyperbilirubinemia.Myocardial zymogram can be used for the diagnosis of the degree of disease and the assessment of treatment effect.

关 键 词：天冬氨酸氨基转移酶 乳酸脱氢酶 肌酸激酶 羧丁酸脱氢酶 肌酸肌酶同功酶 新生儿高胆红素血症 

分 类 号：R446.112[医药卫生—诊断学] R722.17[医药卫生—临床医学]