赣州市人群乙肝感染和免疫状况初步调查  

Preliminary investigation on hepatitis B infection and immune status of people in Ganzhou city

作　　者：陈三仟 古军旺 刘聪[2] 黄彬红[1] 叶桂林 Chen Sanqian;Gu Junwang;Liu Cong(The Gannan Medical College,Ganzhou,Jiangxi 341000;The People's Hospital of Ganzhou City,Ganzhou,Jiangxi 341000)

机构地区：[1]赣南医学院,江西赣州341000 [2]赣州市人民医院,江西赣州341000

出　　处：《基层医学论坛》2021年第29期4248-4250,共3页The Medical Forum

基　　金：赣南医学院校级课题(YB201824)。

摘　　要：目的分析赣州市人群乙肝感染和免疫状况。方法选取赣州市人民医院2014年—2018年诊治的61240例受试者(含住院、门诊患者及体检人员),对受试者的乙肝五项(HBsAg、HBsAb、HBeAg、HBeAb、HBcAb)检测结果进行分析。结果61240例受试者中,HBsAg检测结果为阳性者共计3534例,阳性率为5.77%;男性受试者HBsAg阳性率为6.00%,女性受试者HBsAg阳性率为5.50%,男性HBsAg阳性率明显高于女性(P<0.05)。对年龄分布情况分析,可知41~50岁人群HBsAg阳性率最高,其次为31~40岁、51~60岁,而不足10岁儿童HBsAg阳性率最低。3534例HBsAg阳性患者经进一步检测,其中“小三阳”患者占比最高,为44.88%,其次为“大三阳”患者,占比为39.96%。57706例HBsAg阴性患者中,抗-HBs阳性患者共计41268例,占比71.51%。对疫苗接种情况进行分析,可以发现,年龄不足10岁的儿童,乙肝疫苗接种率为100.00%;随着年龄增长,乙肝疫苗接种率呈现逐渐下降趋势。从人员分布情况来看,城市人口中乙肝疫苗接种率明显高于乡村人口(P<0.05)。结论赣州市人群乙肝感染人数不在少数,且以“小三阳”“大三阳”感染模式最为常见,而41~50岁人群为乙肝感染的高发人群。年龄越大,赣州市人群接种疫苗的概率越低,且乡村人口乙肝疫苗接种率较低,需在乡村中、年龄较大人口中加大乙肝疫苗接种知识宣传,提高疫苗覆盖率。Objective To analyze the hepatitis B infection and immune status of the population in Ganzhou.Methods The 61240 subjects(including inpatients,outpatients and physical examiners)diagnosed and treated by Ganzhou People's Hospital from 2014 to 2018 were selected,and the test results of the subjects'five items of hepatitis B(HBsAg,HBsAb,HBeAg,HBeAb,HBcAb)Perform analysis.Results Among the 61240 subjects,3534 cases were positive for HBsAg,and the positive rate was 5.77%;the positive rate of HBsAg in male subjects was 6.00%the positive rate of HBsAg in female subjects was 5.50%,and the positive rate in males was HBsAg.The rate was significantly higher than that of women(P<0.05).According to the analysis of age distribution,it can be seen that the HBsAg positive rate is the highest among 41~50 years old,followed by 31~40 years old,51~60 years old,and children under 10 years old have the lowest HBsAg positive rate.3534 HBsAg-positive patients were further tested.Among them,the“small three positive”patients accounted for the highest proportion,accounting for 44.88%,followed by the“big three positive”patients,accounting for 39.96%.Among 57706 HBsAg-negative patients,41268 were anti-HBs-positive patients,accounting for 71.51%.Analyzing the vaccination situation,it can be found that the hepatitis B vaccination rate for children under 10 years old is 100.00%;as the age increases,the hepatitis B vaccination rate shows a gradual downward trend.From the perspective of personnel distribution,the hepatitis B vaccination rate in the urban population was significantly higher than that in the rural population(P<0.05).Conclusion There are not a few people infected with hepatitis B in Ganzhou City,and the infection patterns o“f small three positives”and“big three positives”are the most common,and people aged 41~50 are the high-risk groups of hepatitis B infections.The older the age,the lower the probability of vaccinating the population of Ganzhou City,and the lower the rate of hepatitis B vaccination among the rural po

关 键 词：乙肝感染 免疫状况 调查 分析 

分 类 号：R1[医药卫生—公共卫生与预防医学]