艾滋病患者精液和血液中HIV释放和序列差异的研究进展  

Research progress on HIV release and sequence differences in semen and blood of AIDS patients

作　　者：陆珍珍[1] 蓝光华[2] 张景云 林玫[4] LU Zhen-zhen;LAN Guang-hua;ZHANG Jing-yun;LIN Mei(Chronic Disease Institute,Guangxi Center for Disease Prevention and Control,Naning 530028,China)

机构地区：[1]广西壮族自治区疾病预防控制中心慢病所,南宁530028 [2]广西壮族自治区疾病预防控制中心艾防所,南宁530028 [3]解放军总医院第五医学中心泌尿外科,北京100039 [4]广西壮族自治区疾病预防控制中心,南宁530028

出　　处：《传染病信息》2021年第5期468-472,共5页Infectious Disease Information

基　　金：广西自然科学基金课题(2020GXNSFF238044)。

摘　　要：性传播是艾滋病的主要传播途径,有关男性HIV感染者精液和血液中病毒差异的研究也逐渐增多。本文从HIV在精液和血液中释放的规律、HIV在精液和血液中毒株序列的差异尤其是耐药毒株的位点差异,以及产生HIV精、血毒株差异的可能机制进行阐述,为了解男性传播HIV的精、血病毒特性提供参考。The main transmission route of HIV infections is sexual transmission.The researches on viral differences in the semen and blood of HIV infected male patients are gradually increasing.This article summarizes the law of HIV release in semen and blood,the sequence differences of HIV strains in semen and blood,especially the site different of drug-resistant strain,and the possible mechanism of the differences of HIV strains in semen and blood,so as to provide reference for the understanding of HIV viral characteristics in semen and blood through male transmission.

关 键 词：HIV 精液和血液 释放 序列 机制 

分 类 号：R512.91[医药卫生—内科学] R373.51[医药卫生—临床医学]