健康女性阴道微环境及性病病原体感染情况分析  

The Evaluation of Vaginal Micro-ecosystem and Venereal Pathogen Infection Status in Healthy Women

作　　者：魏冰 陆庭嫣[1] 沈俐[1] 杨海鸥[1] 唐振华[1] WEI Bing;LU Ting-yan;SHEN Li;YANG Hai-ou;TANG Zhen-hua(Department of Clinical Laboratory,the International Peace Maternity and Child Health Hospital,Shanghai Jiao tong University School of Medicine,Shanghai,200030,China)

机构地区：[1]上海交通大学医学院附属国际和平妇幼保健院检验科,上海200030

出　　处：《中国初级卫生保健》2021年第10期66-67,70,共3页Chinese Primary Health Care

摘　　要：目的:初步了解上海市健康女性阴道微环境及性病病原体感染情况。方法:选取2018年11月—2019年11月间在上海市某医院进行健康体检和孕前检查的5601名女性,采集其阴道分泌物对阴道微环境、支原体、衣原体和淋球菌进行检测和分析。结果:(1)阴道微环境正常且未检出性病病原体感染女性2573人(45.94%),发生阴道微环境失衡1980人(35.35%)。(2)性病病原体感染率为31.08%,其中解脲支原体阳性1441人(25.73%),人型支原体阳性216人(3.86%),衣原体阳性84人(1.50%),未发现淋病奈瑟氏菌感染者。(3)不同年龄组比较,阴道微环境失衡在31~40岁年龄组检出率最高,解脲支原体和人型支原体感染率均为41~50岁年龄组感染率最高,差异均有统计学意义(χ2值分别为254.09、31.75和26.21,P值均<0.01)。(4)受检女性中共检出混合感染600人(10.71%),以阴道微环境失衡合并解脲支原体感染为主。结论:阴道微环境失衡及性病病原体感染的女性可无明显临床症状,应定期体检,做好预防及治疗工作,并对阴道微环境失衡女性加强病原菌感染的检测。OBJECTIVE To learn vaginal micro-ecosystem and Venereal pathogen infection status in healthy women of Shang⁃hai.METHODS 5601 women were examined and prepregnant in Shanghai hospital between November 2018 and November 2019 and their vaginal secretion samples were collected and detected for vaginal Ureaplasma Urealyticumpositive(UU),Mycoplasma Homi⁃nisconstituent(MH),Chlamydia Trachomatis(CT)and Neisseria Gonorrhea(NG)infection.RESULTS(1)In the 5601 women,vagi⁃nal micro-ecosystem within the normal and not detected venereal pathogen infection of women were 2573 cases with rate of 45.85%.Vaginal micro-ecosystem abnormal were 1980 cases with rate of 35.35%.(2)The rate of sexual pathogen infection was 31.08%,in⁃cluding 1441 positive(25.73%),216 positive(3.86%),84 chlamydia positive(1.50%).No people infected with Neisseria gonorrhoe⁃ae were found.(3)There was statistically significant different with abnormal vaginal micro-ecosystem among different age group,31 to 40 age group was higher.The infection rates of UU and MH in 41-50 years old age group was higher.There was no statistically significant difference in CT infection among different age groups.(4)In all the case mixed infection women were 600(10.71%),the most were abnormal vaginal micro-ecosystem merge with UU infection.CONCLUSION Abnormal vaginal micro-ecosystem and vene⁃real pathogen infection was either asymptomatic,routine physical examination was necessary,which was significant to guide the clini⁃cal prevention and evaluation of vaginal infection.

关 键 词：阴道微环境 解脲支原体 人型支原体 沙眼衣原体 淋病奈瑟菌 

分 类 号：R711.3[医药卫生—妇产科学]