pH和葡萄糖敏感Poly(4-VPBA-co-AA)水凝胶的制备及溶胀性能  

Preparation and Swelling Properties of pH and Glucose-sensitive Poly(4-VPBA-co-AA)Hydrogels

作　　者：杜祥祥 陈恩召 丁松旗 DU Xiangxiang;CHEN Enzhao;DING Songqi(School of Chemistry and Environmental Engineering,Pingdingshan University,Pingdingshan,Henan 467036,China;Nylon New Material Park in High-tech District,Pingdingshan,Henan 467013,China)

机构地区：[1]平顶山学院化学与环境工程学院,河南平顶山467036 [2]平顶山市高新区尼龙新材料园区,河南平顶山467013

出　　处：《平顶山学院学报》2021年第5期38-42,共5页Journal of Pingdingshan University

摘　　要：以丙烯酸(AA)作为pH敏感单体,4-乙烯基苯硼酸(4-VPBA)为葡萄糖敏感单体,过硫酸铵(APS)为引发剂,N,N′-亚甲基双丙烯酰胺(BIS)为交联剂,通过自由基聚合一步法制备了Poly(4-VPBA-co-AA)聚合物水凝胶,通过FT-IR表征了其组成结构,研究了不同葡萄糖浓度和pH下,聚合物水凝胶的溶胀性能.结果表明,水凝胶的溶胀率伴随着葡萄糖浓度的升高而不断增大,在60 mmol/L的葡萄糖溶液中,Poly(4-VPBA-co-AA)聚合物水凝胶的溶胀率达到了1170%.在酸性的条件下和碱性的环境中其溶胀率都比中性的环境大,酸性条件下水凝胶的溶胀率达1735%.Poly(4-VPBA-co-AA)聚合物水凝胶呈现了pH和葡萄糖敏感性.Poly(4-VPBA-co-AA)polymer hydrogels were prepared by free radical polymerization using acrylic acid(AA)as pH-sensitive monomer,4-VPBA as glucose sensitive monomer,ammonium persulfate(APS)as initiator,and N,N′-methylene diacrylamide(BIS)as cross-linking agent.The composition of the polymer hydrogels was characterized by FTIR.The swelling properties of the polymer hydrogels were studied under different glucose concentrations and pH.The results indicate that the swelling rate of hydrogels increases with the glucose concentration,and the swelling rate of Poly(4-VPBA-co-AA)polymer hydrogels reaches 1170%in 60 mmol/L glucose solution.In addition,the swelling rate of as-prepared hydrogels in acidic and alkaline environments is greater than that in neutral environment.The swelling rate under acidic condition is 1735%.Poly(4-VPBA-co-AA)hydrogels exhibit pH and glucose sensitive.

关 键 词：聚合物水凝胶 PH 葡萄糖 溶胀率 

分 类 号：TB381[一般工业技术—材料科学与工程]