Green synthesis of multifunctional carbon dots for anti-cancer and anti-fungal applications  

作　　者：Shaojing Zhao Li Huang Yong Xie Bin Wang Feng Wang Minhuan Lan 

机构地区：[1]Hunan Provincial Key Laboratory of Micro&Nano Materials Interface Science,College of Chemistry and Chemical Engineering,Central South University,Changsha 410083,China [2]State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals R&D Co.,Ltd.,Shenyang 110021,China [3]Key Laboratory of Materials Chemistry for Energy Conversion and Storage of Ministry of Education,Hubei Key Laboratory of Material Chemistry and Service Failure,School of Chemistry and Chemical Engineering,Huazhong University of Science and Technology,Wuhan 430074,China

出　　处：《Chinese Journal of Chemical Engineering》2021年第9期97-104,共8页中国化学工程学报（英文版）

基　　金：supported by the National Natural Science Foundation of China(61805287);Natural Science Foundation of Hunan Province,China(2018JJ3632 and 2019JJ50824);Fundamental Research Funds for State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals Research and Development Co.,Ltd.(2018NYRD02)。

摘　　要：Carbon dots(CDs)have become popular nanomaterials in biomedical and agricultural fields.Herein we synthesized multifunctional CDs which showed anti-cancer and anti-fungal activities.The low cytotoxicity,stable fluorescence and high photothermal conversion efficiency enable the CDs with imagingguided photothermal therapy.The CDs also exhibited intrinsic anti-fungal activity even at a low concentration,i.e.,40 mg·L^(-1) of CDs induced 20%mortality in cucumber downy mildew.Moreover,the largeπ-conjugated nanostructure and the richness of amino and hydroxyl groups make them a powerful delivery platform for flumorph(a fungicide)with a high loading efficiency of 47.18%.Meanwhile,the heat converted from the light can accelerate the release of flumorph from CDs,and thus efficiently kill fungus.

关 键 词：Carbon dots Photothermal therapy Anti-fungus Delivery PESTICIDE 

分 类 号：TQ127.11[化学工程—无机化工] TB383.1[一般工业技术—材料科学与工程]