2009--2019年甘肃省发热伴出疹症候群流行特征  

The epidemiological characteristics of rash and fever syndrome in Gansu Province from 2009 to 2019

作　　者：汪丽娟 刘新凤[2] 周建珲 蒋小娟[2] 袁艳 李娟生[1] 孟蕾[2] WANG Li-juan;LIU Xin-feng;ZHOU Jian-hun;JIANG Xiao-juan;YUAN Yan;LI Juan-sheng;MENG Lei(Department of Epidemiology and Biostatistics,School of Public Health,Lanzhou University,Lanzhou 730000,China;Department of Acute Infectious Disease Prevention and Control,Gansu Provincial Center for Disease Control and Prevention,Lanzhou 730000,China)

机构地区：[1]兰州大学公共卫生学院流行病与卫生统计学研究所,兰州730000 [2]甘肃省疾病预防控制中心急性传染病防制科,兰州730000

出　　处：《中华疾病控制杂志》2021年第9期1102-1106,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家科技重大专项(2017ZX10103006)。

摘　　要：目的了解2009―2019年甘肃省发热伴出疹症候群(rash and fever syndrome,RFS)的病原构成及季节流行性分布特征,为进一步疾病监测和科学防控提供参考。方法采用描述性流行病学方法分析2009―2019年甘肃省RFS病原构成及主要病原的季节性变化特征。结果甘肃省RFS病原构成以病毒为主,主要是肠道病毒(56.04%)、麻疹病毒(19.14%)、水痘-带状疱疹病毒(16.85%)和风疹病毒(7.33%);主要病原在不同年龄段、不同季节间的阳性率差异均有统计学意义(均有P<0.05)。肠道病毒在0~<5岁和5~<15岁组阳性率较高(χ^(2)=393.04,P<0.001),麻疹病毒在35~<50岁组阳性率最高(χ^(2)=150.13,P<0.001),风疹病毒在15~<35岁组阳性率最高(χ^(2)=327.89,P<0.001),而水痘-带状疱疹病毒在0~<5岁组最低(χ^(2)=221.53,P<0.001);冬季肠道病毒阳性率低于其他季节(χ^(2)=173.97,P<0.001);春季麻疹病毒(χ^(2)=164.46,P<0.001)和风疹病毒(χ^(2)=68.90,P<0.001)阳性率较高;而冬季水痘-带状疱疹病毒阳性率高于其他季节(χ^(2)=32.90,P<0.001)。结论2009―2019年甘肃省RFS病原构成以病毒为主,且主要病原具有明显的季节性特征,应对重点人群采取季节性针对性预防措施。Objective To understand the compositions of pathogens and seasonal distribution characteristics of rash and fever syndrome(RFS)in Gansu Province from 2009 to 2019,so as to provide references for further disease surveillance and scientific prevention and control.Methods Descriptive epidemiological methods were used to analyze the composition of pathogens of RFS in Gansu Province from 2009 to 2019 and the seasonal variation characteristics of the main pathogens.Results The compositions of pathogens of RFS in Gansu Province were dominated by viruses,mainly enterovirus(56.04%),measles virus(19.14%),varicella-zoster virus(16.85%)and rubella virus(7.33%).The differences of positive rate of the main pathogens in different age groups and different seasons were statistically significant(all P<0.05).The positive rate of enterovirus was higher in the 0-year-old and 5-year-old groups(χ^(2)=393.04,P<0.001).The positive rate of measles virus was the highest in the 35-year-old group(χ^(2)=150.13,P<0.001).The positive rate of rubella virus was the highest in the 15-year-old group(χ^(2)=327.89,P<0.001),while the varicella-zoster virus had the lowest positive rate in the 0-year-old group(χ^(2)=221.53,P<0.001).The positive rate of enterovirus in winter was lower than those in other seasons(χ^(2)=173.97,P<0.001).The positive rate of measles virus(χ^(2)=164.46,P<0.001)and rubella virus(χ^(2)=68.90,P<0.001)were higher in spring,and the positive rate of varicella-zoster virus in winter was higher than those in other seasons(χ^(2)=32.90,P<0.001).Conclusions From 2009 to 2019,the compositions of pathogens of RFS in Gansu Province were mainly viruses and the main pathogens have obvious seasonal characteristics.Seasonal and targeted proventive methods should be adopted for high-risk populations.

关 键 词：发热伴出疹症候群 病原体 流行特征 甘肃省 

分 类 号：R181.38[医药卫生—流行病学] R183.1[医药卫生—公共卫生与预防医学]