中药汤剂煎煮工艺标准化与个性化结合方法探索  

Exploration on the Method Combining Standardization and Individuation in Decoction Process of Traditional Chinese Medicine Decoction

作　　者：李海洋 桂新景 岳佑凇 侯富国 王艳丽[2,3,4] 王小鹏 郭晓帆 李学林 刘瑞新[2,3,4,5,6,7] LI Haiyang;GUI Xinjing;YUE Yousong;HOU Fuguo;WANG Yanli;WANG Xiaopeng;GUO Xiaofan;LI Xuelin;LIU Ruixin(School of Pharmacy,Henan University of Chinese Medicine,Zhengzhou 450046,China;Department of Pharmacy,the First Af liated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;Level 3 Laboratory of Traditional Chinese Medicine Preparations,National Administration of Traditional Medicine,Zhengzhou 450000,China;Henan Engineering Research Center for Modernization of Clinical Application of Chinese Herbal Pieces,Zhengzhou 450000,China;Co-construction Collaborative Innovation Center For Chinese Medicine and Respiratory Diseases by Henan&Education Ministry of P.R.China,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China;Henan Key Laboratory for Clinical Pharmacy of Traditional Chinese Medicine,Zhengzhou 450000,China;Henan Engineering Laboratory for Clinical Evaluation Techniques of Traditional Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学药学院,郑州450046 [2]河南中医药大学第一附属医院药学部,郑州450000 [3]国家中医药管理局中药制剂三级实验室,郑州450000 [4]河南省中药饮片临床应用现代化工程研究中心,郑州450000 [5]河南中医药大学呼吸疾病中医药防治省部共建协同创新中心,郑州450046 [6]河南省中药临床药学中医药重点实验室(建设单位),郑州450000 [7]河南省中药临床评价技术工程实验室,郑州450000

出　　处：《医药导报》2021年第11期1561-1567,共7页Herald of Medicine

基　　金：国家重点研发计划中医药现代化重点专项(2017YFC1703400);国家重点研发计划中医药现代化重点专项课题(2017YFC1703401,2017YFC1703402);国家自然科学基金资助项目(81773892,81774452);河南省中医药拔尖人才培养项目(重点项目)(2019ZYBJ07);河南省高层次人才特殊支持“中原千人计划”-“中原青年拔尖人才”项目(ZYQR201912158)。

摘　　要：中药汤剂是临床应用历史最久、应用最广范的剂型,具有可随证加减、起效快、易吸收等特点。汤剂煎煮作为中药进入人体发挥治疗作用前的最后环节,其质量优劣直接关系到中药临床疗效。传统煎药可根据不同处方的个性化需求调整煎药工艺,但煎药质量因个人经验而异;现代化煎药因规模化生产对特殊煎煮的要求有所降低,多表现为煎药同质化。中药汤剂煎煮工艺的标准化对于规范汤剂煎煮过程,减少主观因素所致煎药质量差异有重要意义,而个性化是中医药辨证论治特点的重要体现,两者缺一不可。因此,探索中药汤剂煎煮工艺标准化和个性化结合,实现两者有机融合,对推动中医药产业可持续发展尤为重要。Traditional Chinese medicine decoction is one of the most widely used dosage forms with the longest clinical application history.It has the characteristics of modification according to syndrome,taking effect quickly,and absorbing easily.As the last link before Chinese medicine enters the human body to play its therapeutic role,the quality of decoction is directly related to the clinical efficacy of Chinese medicine.Traditional decocting technology can be adjusted according to the personalized needs of different prescriptions,but the quality of decoction varies with personal experience.Due to the needs of large-scale production,the requirements for special decocting in the process of modern decocting are reduced,which is mainly manifested as homogenization of decoction.The standardization of decoction process of traditional Chinese medicine is of great significance to standardize the decoction process and reduce the quality difference of decoction caused by subjective factors,while personalization is an important manifestation of the characteristics of syndrome differentiation and treatment of traditional Chinese medicine,and both are indispensable.Therefore,it is particularly important to explore the method of combining standardization and personalization of decoction process of traditional Chinese medicine and realize the organic integration of the two,which is particularly important to promote the sustainable development of traditional Chinese medicine industry.

关 键 词：中药汤剂 煎煮工艺 标准化 个性化 

分 类 号：R286[医药卫生—中药学] R927.1[医药卫生—中医学]